Ride comfort is an important factor to measure the performance of automobiles. The research presented in this paper investigates the effects of parameters related to suspension, wheels and tires on ride comfort. A seven freedom degrees model is established for automobiles, and the corresponding simulation model is also given. An actual automobile is taken as example to simulate its acceleration based on the above models. In addition, ride comfort simulation comparison of three types of vehicles from different manufacturers has been conducted. The outcome of the research provide useful tools for designers to optimize their automobile structure parameters to improve the design efficiency and accuracy.