This paper aims at structure strength analysis which makes the static and dynamic analysis for the numerical control abrasive belt grinding machine from key components to the whole machine and obtains relevant data and conclusions. On the base of the original structure, according to the design requirements, the important parts of the grinding machine are simplified and mechanical analysis. According to the calculated results and the constraints of the machine, the mathematical modeling of key components and the limit position can be obtained by using the mathematical theory of mechanical optimization. According to the results, the entity model and static analysis can be finished. Finally, the static and modal analysis of the large grinding equipment can be carried on the FEA software and draw some important conclusions.