Study on Low-Temperature Deposition Manufacturing Process Parameters of Three-Dimensional Chitosan Scaffold

Yuan Yuan Liu; Shu Hui Fang; Zhen Zhong Han; Ying Liu; Da Li Liu; Qing Xi Hu

doi:10.4028/www.scientific.net/KEM.522.97

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The Research on a New Feeding Device of Low-Temperature Deposition for Fabricating Tissue Engineering Scaffolds
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Study on Low-Temperature Deposition Manufacturing Process Parameters of Three-Dimensional Chitosan Scaffold
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HomeKey Engineering MaterialsKey Engineering Materials Vol. 522Study on Low-Temperature Deposition Manufacturing...

Study on Low-Temperature Deposition Manufacturing Process Parameters of Three-Dimensional Chitosan Scaffold

Abstract:

From the perspective of forming bone scaffold, the technologic parameters of LDM which have important influence on the shape of the deposition material are studied. Through building experimental platform and using chitosan solution as experimental material, the influence of the temperature and the layer height on the lap of every fiber layer are firstly discussed in detail. Besides, the effects of nozzle diameter, the velocity of receiving device, the pressure of feeding device are also discussed. Then the above mentioned process parameters are all optimized, which make the forming mechanism of LDM to be clear. Finally, based on the optimal parameters, the scaffold with self-designed pore size and a high degree of pore interconnectivity, which meeting the requirements of the structure of tissue engineering are fabricated.

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Periodical:

Key Engineering Materials (Volume 522)

Pages:

97-102

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.522.97

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Online since:

August 2012

Authors:

Yuan Yuan Liu, Shu Hui Fang, Zhen Zhong Han, Ying Liu, Da Li Liu, Qing Xi Hu

Keywords:

Adhesion, Bone Scaffold, Low-Temperature Deposition Manufacturing (LDM)

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