Study of Bone Restoration Ca-Si-Zn Complex

Ren Jei Chung; Huey Yuan Wang; Kai Shiang Chen; Huan Yu Wu

doi:10.4028/www.scientific.net/KEM.587.427

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Bridging and Repairing Patient Specific Acetabular Defects with a New Custom Acetabular Cage
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Biomechanics of Vertebroplasty: Effect of Cement Viscosity on Mechanical Behaviour
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Osteoconductive Bone Substitutes as Treatment of Benign Lytic Lesions
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Study of Bone Restoration Ca-Si-Zn Complex
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CAD Method for Profiling Helical Surfaces of Parts Used in the Orthopaedic Reconstruction Surgery
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Radiographic Analysis of Bone Remodeling around Hydroxyapatite Coated Femoral Stems
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HomeKey Engineering MaterialsKey Engineering Materials Vol. 587Study of Bone Restoration Ca-Si-Zn Complex

Study of Bone Restoration Ca-Si-Zn Complex

Abstract:

In this research, the purpose is to carry out the in vitro study of the plasticity hybrid complex. The main components of the material are tricalcium silicate (C₃S, Ca₃SiO₅) and collagen. In vitro studies, including cell toxicity test (MTT), flowcytometry detection and alkaline phosphatase test (ALP) were carried out to evaluate the biocompatibility of the materials and soaking mediums. Results showed that soaking mediums of different amounts of materials didn’t affect cell growth harmfully. Moreover, the soaking mediums would stimulate the osteoblast and trigger the biomineralization processes leading to higher secretion of ALP during cultivation.. The results in this research showed that the biocompatibility of our hybrid complex for future applications.

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Periodical:

Key Engineering Materials (Volume 587)

Pages:

427-430

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.587.427

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Online since:

November 2013

Authors:

Ren Jei Chung*, Huey Yuan Wang, Kai Shiang Chen, Huan Yu Wu

Keywords:

Collagen, In Vitro Study, Plasticity Hybrid Complex, Tricalcium Silicate

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References

[1] D.M. Reffitt, N. Ogston, R. Jugdaohsingh, H.F.J. Cheung, B.A.J. Evans, R.P.H. Thompson, J.J. Powell and G.N. Hampson, Bone, 32 : 127-135. (2003).

DOI: 10.1016/s8756-3282(02)00950-x

Google Scholar

[2] R.J. Chung, T.S. Chin, C.W. Huang, P.C. Lin, T.J. Hsu and F.I. Chou, Key Engineering Materials, 240: 337-340. (2003).

Google Scholar

[3] M.J. Shamblott, J. Axelman, S. Wang, E.M. Bugg, J.W. Littlefield, P.J. Donovan, P.D. Blumenthal, G.R. Huggins and J.D. Gearhart, P. Natl. Acad. Sci. USA, 96: 1162. (1999).

DOI: 10.1073/pnas.95.23.13726

Google Scholar