A Novel Approach for the Synthesis of PEGylated Monodispersed Superparamagnetic Iron Oxide Nanoparticles

Abstract:

PEGylated, monodispersed, superparamagnetic, iron oxide nanoparticles (Fe₃O₄ / γ-Fe₂O₃) were synthesized by using a novel metal-organic approach in three steps. Ferric nitrate nonahydrate, Fe (NO₃)₃^.9H₂O, was used as iron source, which was sterically hindered among the interstices and / or in the cavities of β-Cyclodextrin (β-CD) molecules, following a modified complexation procedure. Via a polyol process the obtained complex system was first dispersed in polyethylene glycol (PEG) and under mild thermal treatment and in the presence of 1,12 dodecanediol, a new complex system of carboxylate type was formed, between ferric nitrate and PEG, denoted Fe (NO₃)₃^.9H₂O-PEG. This metal-organic precursor was thermally decomposed, forming the iron oxide nanoparticles. The obtained particles were characterized by X-ray diffraction spectroscopy (XRD), Fourier Transform Infrared spectroscopy (FTIR) and transmission electron microscopy (TEM).

• Periodical: Key Engineering Materials (Volume 605)
• Pages: 693-696
• DOI: https://doi.org/10.4028/www.scientific.net/KEM.605.693
• Online since: April 2014
• Authors: P. Tserotas*, E. Statharas, Ioannis Kartswnakis
• Keywords: Cyclodextrins, Maghemite, Magnetic Nanoparticles, Magnetite, Surfactant

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