Preparation of α-Tricalcium Phosphate Powders Surface-Modified with Inositol Phosphate for Cement Fabrication

Toshiisa Konishi; Michiyo Honda; Tomohiko Yoshioka; Satoshi Hayakawa; Mamoru Aizawa

doi:10.4028/www.scientific.net/KEM.631.113

Paper Titles

Synthesis of Peroxyapatite by Hydrothermal Processing
p.88

Synthesis of Tetracalcium Phosphate at Reduced Temperatures
p.93

Effect on Drying Conditions on Amorphous Calcium Phosphate
p.99

Biocompatibility of Silver-Containing Calcium-Phosphate Cements with Anti-Bacterial Properties
p.107

Preparation of α-Tricalcium Phosphate Powders Surface-Modified with Inositol Phosphate for Cement Fabrication
p.113

The Effects of Nanoparticles of Silica and Alumina on Flow Ability and Compressive Strength of Cementitious Composites
p.119

Effect of Particle Size on Carbonate Apatite Cement Properties Consisting of Calcite (or Vaterite) and Dicalcium Phosphate Anhydrous
p.128

Bioceramic Production from Giant Purple Barnacle (Megabalanus tintinnabulum)
p.137

Colour Stability of Self-Adhesive Flowable Composites before and after Storage in Water
p.143

HomeKey Engineering MaterialsKey Engineering Materials Vol. 631Preparation of α-Tricalcium Phosphate Powders...

Preparation of α-Tricalcium Phosphate Powders Surface-Modified with Inositol Phosphate for Cement Fabrication

Abstract:

We have previously developed biodegradable β-tricalcium phosphate (β-TCP) cement based on the chelate-setting mechanism of inositol phosphate (IP6). The β-TCP cement powder for the cement fabrication was prepared via a novel powder preparation process, in which the starting β-TCP powders were prepared by simultaneous ball-milling and surface-modification in the IP6 solution. In the present study, the novel powder preparation process was applied to an α-TCP powder, and effect of milling time and beads size for ball-milling on the material properties of the α-TCP powders was investigated. The α-TCP powder ball-milled in 1000 ppm IP6 solution for 4 h with 2 mm-diameter beads was composed of single phase α-TCP with the smallest particle size of 2.2 µm. Dissolution of 4 h-milled α-TCP powder was approximately twice higher than that of starting α-TCP powder before ball-milling. The α-TCP powder with high dissolution property prepared via the novel powder preparation process is potential candidate for fabrication of the chelate-setting cement.

You might also be interested in these eBooks

View Preview

Info:

Periodical:

Key Engineering Materials (Volume 631)

Pages:

113-118

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.631.113

Citation:

Cite this paper

Online since:

November 2014

Authors:

Toshiisa Konishi*, Michiyo Honda, Tomohiko Yoshioka, Satoshi Hayakawa, Mamoru Aizawa

Keywords:

Calcium-Phosphate Cement, Inositol Phosphate, Surface Modification, α-Tricalcium Phosphate

Export:

RIS, BibTeX

Price:

Permissions CCC:

Request Permissions

Permissions PLS:

Request Permissions

Сopyright:

Citation:

* - Corresponding Author

References

[1] H. Monma, T. Kanazawa, The hydration of α-tricalcium phosphate, Yogyo-Kyokai-Shi. 8 (1976) 209–213.

Google Scholar

[2] W. E. Brown, L. C. Chow, U.S. Patent, 4, 518, 430. (1985).

Google Scholar

[3] Y. Miyamoto, K. Ishikawa, M. Takechi, T. Toh, T. Yuasa, M. Nagayama, K. Suzuki, Histological and compositional evaluations of three types of calcium phosphate cements when implanted in subcutaneous tissue immediately after mixing, J. Biomed. Mater. Res. 48 (1999).

DOI: 10.1002/(sici)1097-4636(1999)48:1<36::aid-jbm8>3.0.co;2-i

Google Scholar

[4] M. Aizawa, Y. Haruta, I. Okada, Development of novel cement processing using hydroxyapatite particles modified with inositol phosphate, Arch. BioCeram. Res. 3 (2003) 134–138.

Google Scholar

[5] Y. Horiguchi, Y. Yoshikawa, K. Oribe, M. Aizawa, Fabrication of chelate-setting hydroxyapatite cements from four kinds of commercially-available powder with various shape and crystallinity and their mechanical property, J. Ceram. Soc. Jpn. 116 (2008).

DOI: 10.2109/jcersj2.116.50

Google Scholar

[6] T.H. Dao, Polyvalent cation effects on myo-inositol hexakis dihydrogenphosphate enzymatic dephosphorylation in dairy wastewater, J. Environ. Qual. 32 (2003) 694–701.

DOI: 10.2134/jeq2003.6940

Google Scholar

[7] C.J. Martin, W.J. Evans, Phytic acid-metal ion interactions. II. The effect of pH on Ca(II) binding, J. Inorg. Biochem. 27 (1986) 17–30.

DOI: 10.1016/0162-0134(86)80105-2

Google Scholar

[8] T. Konishi, Z. Zhuang, M. Mizumoto, M. Honda, M. Aizawa, Fabrication of chelate-setting cement from hydroxyapatite powder prepared by simultaneously grinding and surface-modifying with sodium inositol hexaphosphate and their material properties, J. Ceram. Soc. Jpn. 120 (2012).

DOI: 10.2109/jcersj2.120.159

Google Scholar

[9] H. Oonishi, L.L. Hench, J. Wilson, F. Sugihara, E. Tsuji, S. Kushitani, H. Iwaki, Comparative bone growth behavior in granules of bioceramic materials of various sizes, J. Biomed. Mater. Res., 44 (1999) 31–43.

DOI: 10.1002/(sici)1097-4636(199901)44:1<31::aid-jbm4>3.0.co;2-9

Google Scholar

[10] U. Gbureck, J.E. Barralet, L. Radu, H.G. Klinger, R. Thull, Amorphous α-tricalcium phosphate: preparation and aqueous setting reaction, J. Am. Ceram. Soc. 87 (2004) 1126–1132.

DOI: 10.1111/j.1551-2916.2004.01126.x

Google Scholar

[11] T. Konishi, S. Takahashi, Z. Zhuang, K. Nagata, M. Mizumoto, M. Honda, Y. Takeuchi, H. Matsunari, H. Nagashima, M. Aizawa, Biodegradable β-tricalcium phosphate cement with anti-washout property based on chelate-setting mechanism of inositol phosphate, J. Mater. Sci. Mater. Med. 24 (2013).

DOI: 10.1007/s10856-013-4903-8

Google Scholar

[12] C. Durucan, P.W. Brown, Reactivity of α-tricalcium phosphate, J. Mater. Sci. 37 (2002) 963–969.

Google Scholar

[13] F. Grynspan, M. Cheryan, Calcium phytate: Effect of pH and molar ratio on in vitro solubility, J. Am. Oil Chem. Soc. 60 (1983) 1761–1764.

DOI: 10.1007/bf02680350

Google Scholar