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HomeKey Engineering MaterialsKey Engineering Materials Vol. 631Fabrication of Hydroxyapatite Microcapsule...

Fabrication of Hydroxyapatite Microcapsule Containing Vitamin B₁₂ for Sustained-Release

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Abstract:

When either the pH or temperature of simulated body fluid (SBF) are raised, fine particles of calcium phosphate are precipitated. We found that these fine particles actively induce hydroxyapatite formation from body fluid or SBF and named the particles Apatite Nuclei. In this study, we fabricated hollow hydroxyapatite microcapsules by using Apatite Nuclei. We inserted vitamin B₁₂ in the hollow microcapsule and examined thesustained-release properties.

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Bioceramics 26

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Periodical:

Key Engineering Materials (Volume 631)

Pages:

326-331

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.631.326

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Online since:

November 2014

Authors:

Takeshi Yabutsuka*, Kazuma Iwahashi, Hiroki Nakamura, Takeshi Yao

Keywords:

Apatite Nucleus (AN), Hydroxyapatite Microcapsule, Sustained-Release, Vitamin B₁₂

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© 2015 Trans Tech Publications Ltd. All Rights Reserved

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