Electrophoretic Deposition of Porous Ti Coatings for Bone Implants: In Vitro and In Vivo Evaluation

Abstract:

A new powder metallurgical processing route for porous Ti coatings on Ti-6Al-4V substrates based on the electrophoretic deposition (EPD) of TiH₂ suspensions is presented. After dehydrogenation and sintering in vacuum, coatings with a fully interconnected porosity (up to 51%, interconnective pore channels (IPC) of 2-50 µm) and high adhesion strength (up to 47 MPa) are obtained. Further evaluation of these coatings for potential use in biomedical implants shows that EPD Ti coatings are significantly less prone to bacterial adhesion compared to state-of-the-art vacuum plasma sprayed (VPS) coatings, while still allowing substantial bone ingrowth. Using EPD, the coating process can easily be transferred to complex-shaped implant components.

• Periodical: Key Engineering Materials (Volume 654)
• Pages: 144-148
• DOI: https://doi.org/10.4028/www.scientific.net/KEM.654.144
• Online since: July 2015
• Authors: Annabel Braem*, Bram Neirinck, Omer Van der Biest, Jef Vleugels
• Keywords: Biofilm Formation, Bone Ingrowth, Microporosity, Porous Ti Coatings, Powder metallurgy, Staphylococci, Surface Functionalization

References

[1] Data obtained from the Norwegian Arthroplasty Register: Annual report 2010. http: /nrlweb. ihelse. net [accessed on 31/08/2011].

[2] K. Bozic, S. Kurtz, E. Lau, K. Ong, T. Vail, D. Berry, The epidemiology of revision total hip arthroplasty in the United States, J. Bone Joint Surg. Am. 91 (2009) 128-133.

DOI: 10.2106/jbjs.h.00155

[3] K. Bozic, S. Kurtz, E. Lau, K. Ong, V. Chiu, T. Vail, H. Rubash, D. Berry, The epidemiology of revision total knee arthroplasty in the United States, Clin. Orthop. Relat. Res. 468 (2010) 45-51.

DOI: 10.1007/s11999-009-0945-0

[4] G. Ryan, A. Pandit, D.P. Apatsidis, Fabrication methods of porous metals for use in orthopaedic applications, Biomaterials 27 (2006) 2651–2670.

DOI: 10.1016/j.biomaterials.2005.12.002

[5] A. Braem, T. Mattheys, B. Neirinck, Schrooten, J., O. Van der Biest, J. Vleugels, Porous titanium coatings through electrophoretic deposition of TiH2 suspensions, Adv. Eng. Mater. 13 (2011) 509-515.

DOI: 10.1002/adem.201100011

[6] T. Mattheys, A. Braem, B. Neirinck, O. Van der Biest, J. Vleugels, Porous Ti coatings for implant fixation by electrophoretic deposition of TiH2 particle stabilised emulsions, Adv. Eng. Mater. 14 (2012) 371-376.

DOI: 10.1002/adem.201100250

[7] A. Braem, L. Van Mellaert, T. Mattheys, D. Hofmans, E. De Waelheyns, L. Geris, J. Anné, J. Schrooten, J. Vleugels, Staphylococcal biofilm growth on smooth and porous titanium coatings for biomedical applications, J. Biomed. Mater. Res. A . 102 (2014).

DOI: 10.1002/jbm.a.34688

[8] A. Braem, A. Chaudhari, M. Vivan Cardoso, J. Schrooten, J. Duyck, J. Vleugels, Peri- and intra-implant bone response to microporous Ti coatings with surface modification, Acta Biomater. 10 (2014) 986-995.

DOI: 10.1016/j.actbio.2013.10.017

[9] S. Bouazza, E. Fuchs, A. Rosin, M. Willert-Porada, Synthesis and properties of graded porous Ti-TiO2 multifunctional composites obtained by different processing methods, Mater. Sci. Forum 631-632 (2010) 141-146.

DOI: 10.4028/www.scientific.net/msf.631-632.141

[10] B. Neirinck, T. Mattheys, A. Braem, J. Fransaer, O. Van der Biest, J. Vleugels, Porous titanium coatings obtained by electrophoretic deposition (EPD) of Pickering emulsions and microwave sintering, Adv. Eng. Mater. 10 (2008) 246-249.

DOI: 10.1002/adem.200700273