Synthesis and Characterization of Artificial Bone Material Using Calcium from a Natural Source

Abstract:

Hydroxyapatite (HAp), with chemical formula of Ca₁₀(PO₄)₆(OH)₂,is one of the most popular biomaterials applied as a scaffold or a scaffold component in bone tissue engineering. Synthesis of this material using calcium from a natural sourcewill be a good strategy for cost reduction. Waste cockle shells containing abundance of nearly pure calcium carbonate (CaCO₃) are ideal sources of calcium. In this study, the waste cockle shells were turned to CaO nanoparticles using a simple chemical route. The CaO nanoparticle was used as a starting material to react with hydrous and anhydrous calcium hydrogen phosphate (CaHPO₄) with calcium-to-phosphate (Ca/P) ratios in the range of1.5-1.67 under a mechanochemical process. The synthesized products were characterized by X-ray diffraction technique and scanning electron microscope.The experimental results revealed that under the same reaction timethe reaction using the dehydrated CaHPO₄yielded a mixture ofHApand residual CaHPO₄whereas the reaction using hydratedCaHPO₄(CaHPO₄.2H₂O) yieldeda mixture of HApand beta tricalcium phosphate (β-TCP). The HAp yields of the reactions using dehydrated and hydratedCaHPO₄were 71% and 51 %, respectively.

• Periodical: Key Engineering Materials (Volume 659)
• Pages: 40-44
• DOI: https://doi.org/10.4028/www.scientific.net/KEM.659.40
• Online since: August 2015
• Authors: Poj Chutong*, Nuchthana Poolthong, Ruangdaj Tongsri
• Keywords: Biomaterials, CaO Nanoparticles, Hydroxyapatite, Mechanochemical Process

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