Luminescent Materials on the Basis of Yttrium Oxide and Yttrium Aluminum Garnet Used for Photodynamic Therapy

Abstract:

Finely-dispersed phosphors of Y₂O₃:Eu and Y₃Al₅O₁₂:Eu have been synthesized with the help of Pechini method and the method of self-propagating high-temperature synthesis (SHS). During the synthesis of phosphors on the basis of Y₂O₃ carried out with Pechini method the size of crystallites increases with the enlargement of concentration of yttrium, but it decreases when the method of SHS is applied. The structure of phosphors on the basis of Y₃Al₅O₁₂ (YAG) is strongly amorphized. This fact agrees with the data of XRD and with the prevalence of the band with λ_max = 613 nm in the spectra of this phosphor. The enlargement of yttrium concentration in it promotes the amorphisation of yttrium aluminum garnet and the decrease of a crystal phase content. The sample of Y₃Al₅O₁₂:Eu synthesized with Pechini method has the maximum intensity, while in conditions of excitement with “high-level” X-ray radiation which corresponds to the radiation of industrial medical X-ray apparatus, the phosphor of Y₂O₃:Eu synthesized with the help of SHS showed the largest intensity. Colloid solutions prepared with the use of the samples synthesized by SHS method revealed a higher steadiness and a lower disposition to the sedimentation process. The samples of Y₂O₃:Eu phosphor possessing the smallest size of particles and the highest intensity of X-ray luminescence are the most suitable for the creation of pharmacological drugs used for photodynamic therapy.

• Periodical: Key Engineering Materials (Volume 670)
• Pages: 232-238
• DOI: https://doi.org/10.4028/www.scientific.net/KEM.670.232
• Online since: October 2015
• Authors: Vadim V. Bakhmetyev*, Lev A. Lebedev, Anna B. Vlasenko, Sergey P. Bogdanov, Alexander E. Sovestnov, Tamara S. Minakova, Ludmila Yu. Minakova, Maxim М. Sychov
• Keywords: Luminescent Materials, Phosphor, Photoluminescence (PL), Sol-Gel Method, SURF, X-Ray Luminescence, Yttrium Aluminum Garnet, Yttrium Oxide

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