Physical Justification of an Increase in the Efficacy of Radiofrequency Systems for Myocardial Ablation

Article Preview

Abstract:

The article presents data on dependence of the myocardial electrical impedance on the temperature. These data have high clinical relevance because radio frequency energy-induced destruction of the myocardium in the course of surgical treatment of cardiac arrhythmias should be performed transmurally. Insufficient transmural myocardial damage results in recurrence of cardiac arrhythmias. Therefore, achieving transmural treatments of the myocardium is of high significance.Studies were performed by using 20 isolated hearts. To evaluate the effectiveness of radio frequency exposure, we studied two temperature settings: myocardial normothermia (36.6 °C) and myocardial hypothermia (20 °C). The depth of destruction as well as the temperatures of the epicardial, endocardial, and intramural myocardium at the points of impact were estimated. Data showed that lower temperature decreases tissue electrical impedance and results in a greater depth of damage.

You might also be interested in these eBooks

Info:

Periodical:

Pages:

432-435

Citation:

Online since:

February 2016

Export:

Price:

Permissions CCC:

Permissions PLS:

Сopyright:

© 2016 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

[1] D.K. Swanson, W.J. Smith, T. Ibrahim, et al. Tissue temperature feedback control of power: the key to successful ablation. Innovations (Phila). 6, 4 (2011) 276-282.

DOI: 10.1097/imi.0b013e31822b4d22

Google Scholar

[2] M. La Meir, S. Gelsomino, F. Lucà, et al. Minimally invasive thoracoscopic hybrid treatment of lone atrial fibrillation: early results of monopolar versus bipolar radiofrequency source. Interact Cardiovasc Thorac Surg. 14, 4 (2012) 445-450.

DOI: 10.1093/icvts/ivr142

Google Scholar

[3] D. Chang, S. Zhang, D. Yang, et al. Effect of epicardial fat pad ablation on acute atrial electrical remodeling and inducibility of atrial fibrillation. Circ J. 74, 5 (2010) 885-894.

DOI: 10.1253/circj.cj-09-0967

Google Scholar

[4] W. Saliba, O.M. Wazni Sinus rhythm restoration and treatment success: insight from recent clinical trials. Clin Cardiol. 34, 1 (2011) 12-22.

DOI: 10.1002/clc.20826

Google Scholar

[5] C. Wenning, P.S. Lange, C. Schülke, et al. Pulmonary vein isolation in patients with paroxysmal atrial fibrillation is associated with regional cardiac sympathetic denervation. EJNMMI Res. 3, 1(2013) 81.

DOI: 10.1186/2191-219x-3-81

Google Scholar

[6] G. Nasso, R. Bonifazi, A. Del Prete, et al. Long-term results of ablation for isolated atrial fibrillation through a right minithoracotomy: toward a rational revision of treatment protocols. J Thorac Cardiovasc Surg. 142, 2 (2011) e41-e46.

DOI: 10.1016/j.jtcvs.2011.04.009

Google Scholar

[7] S. Nath, D.E. Haines Biophysics and pathology of catheter energy delivery systems. Prog Cardiovasc Dis. 37, 4 (1995) 185-204.

Google Scholar

[8] S. Nath, C. Lynch 3rd, J.G. Whayne et al. Cellular electrophysiological effects of hyperthermia on isolated guinea pig papillary muscle. Implications for catheter ablation. Circulation. 88(4 Pt 1) (1993) 1826-1831.

DOI: 10.1161/01.cir.88.4.1826

Google Scholar

[9] S. Nath, J.G. Whayne, S. Kaul, et al. Effects of radiofrequency catheter ablation on regional myocardial blood flow. Possible mechanism for late electrophysiological outcome. Circulation. 89, 6 (1994) 2667-2672.

DOI: 10.1161/01.cir.89.6.2667

Google Scholar