Biodegradation of Poly(3-Hydroxybutyrate) and Poly(3-Hydroxybutyrate-Co-3-Hydroxy-4-Methylvalerate) Films by Porcine Pancreatic Lipase

Abstract:

Article Preview

In the current work, the degradation of poly (3-hydroxybutyrate) (PHB) and poly (3-hydroxybutyrate-co-3-hydroxy-4-methylvalerate) (PHB4MV) films was studied in vitro by pancreatic lipase. The changes in film properties were traced by several analytical methods: the change of weight, molecular weight, and Young’s modulus (by nanoindentation) were measured. During the six months of polymer films degradation the weight of samples decreased slightly, while a great increase in Young's modulus due to the relatively fast degradation of the amorphous areas was observed, as well as molecular weight of polymers decreased significantly. Weight loss of PHB4MV is faster than degradation rate of PHB, but the molecular weight of PHB 1700 decrease rapidly than PHB4MV; the Young’s modulus of polymers remained relatively unchanged.

Info:

Periodical:

Edited by:

Marina Polyakova

Pages:

57-63

Citation:

V. Zhuikov et al., "Biodegradation of Poly(3-Hydroxybutyrate) and Poly(3-Hydroxybutyrate-Co-3-Hydroxy-4-Methylvalerate) Films by Porcine Pancreatic Lipase", Key Engineering Materials, Vol. 779, pp. 57-63, 2018

Online since:

September 2018

Export:

Price:

$38.00

* - Corresponding Author

[1] A.P. Bonartsev, G.A. Bonartseva, K.V. Shaitan, M.P. Kirpichnikov, Biochemistry Supplement Series B: Biomedical Chemistry Vol. 5 (2011), p.10–21.

[2] M.I. Artsis, A.P. Bonartsev, A.L. Iordanskii, G.A. Bonartseva, G.E. Zaikov, Molecular Crystals and Liquid Crystals Vol. 523 (2010), pp.21-49.

DOI: https://doi.org/10.1080/15421401003726519

[3] G.-Q. Chen, Q. Wu, Biomaterials Vol. 26 (2005), pp.6565-6578.

[4] A.P. Bonartsev, G.A. Bonartseva, T.K. Makhina, V.L. Myshkina, E.S. Luchinina, V.A. Livshits, A.P. Boskhomdzhiev, V.S. Markin, A.L. Iordanskii, Applied biochemistry and microbiology Vol. 42 (2006), pp.625-630.

DOI: https://doi.org/10.1134/s0003683806060159

[5] A.A. Olkhov, O.V. Staroverova, A.P. Bonartsev, I.I. Zharkova, E.D. Sklyanchuk, A.L. Iordanskii, S.Z. Rogovina, A.A. Berlin, A.A. Ishchenko, Polymer Science, Series D. Glues and Sealing Materials Vol. 8 (2015), p.100–109.

DOI: https://doi.org/10.1134/s1995421215020124

[6] A.P. Bonartsev, I.I. Zharkova, S.G. Yakovlev, V.L. Myshkina, T.K. Makhina, A.L. Zernov, K.S. Kudryashova, A.V. Feofanov, E.A. Akulina, E.V. Ivanova, V.A. Zhuikov, A.V. Volkov, N.V. Andreeva, V.V. Voinova, G.A. Bonartseva, K.V. Shaitan, M.P. Kirpichnikov, Journal of Biomaterials and Tissue Engineering Vol. 6 (2016).

DOI: https://doi.org/10.1166/jbt.2016.1492

[7] E.R. Pavlova, D.V. Bagrov, M.N. Kopitsyna, D.A. Shchelokov, A.P. Bonartsev, I.I. Zharkova, T.K. Mahina, V.L. Myshkina, G.A. Bonartseva, K.V. Shaitan, D.V. Klinov. Poly(hydroxybutyrate-co-hydroxyvalerate) and bovine serum albumin blend prepared by electrospinning. J. Appl. Polym. Sci. (2017).

DOI: https://doi.org/10.1002/app.45090

[8] V.A. Livshits, A.P. Bonartsev, A.L. Iordanskii, E.A. Ivanov, T.A. Makhina, V.L. Myshkina, G.A. Bonartseva, Polymer Science Series B Vol. 51 (2009), pp.256-263.

DOI: https://doi.org/10.1134/s1560090409070082

[9] E.V. Filatova, S.G. Yakovlev, A.P. Bonartsev, T.K. Mahina, V.L. Myshkina, G.A. Bonartseva, Applied Biochemistry and Microbiology Vol. 48 (2012), pp.598-602.

[10] A.P. Bonartsev, S.G. Yakovlev, E.V. Filatova, G.M. Soboleva, T.K. Makhina, G.A. Bonartseva, K.V. Shaitan, V.O. Popov, M.P. Kirpichnikov, Biochemistry Supplement Series B: Biomedical Chemistry Vol. 6 (2012), p.42–47.

DOI: https://doi.org/10.1134/s1990750812010027

[11] A.P. Bonartsev, A.L. Zernov, S.G. Yakovlev, I.I. Zharkova, V.L. Myshkina, T.K. Mahina, G.A. Bonartseva, N.V. Andronova, G.B. Smirnova, J.A. Borisova, M.S. Kalishjan, K.V. Shaitan, H.M. Treshalina. Anti-Cancer Agents in Medicinal Chemistry Vol. 17 (2017).

DOI: https://doi.org/10.2174/1871520615666160504095433

[12] N.P. Ermakova, A.P. Bonartsev, A.L. Zernov, O.I Konyaeva, N.Y. Kulbachevskaya, I.B Merkulova, T.V. Abramova, V.A. Chaley, S.G. Yakovlev, G.A. Bonartseva, K.V. Shaitan, V.M. Bukhman. Anti-Cancer Agents in Medicinal Chemistry Vol. 17 (2017).

DOI: https://doi.org/10.2174/1871520616666160817104529

[13] A.L. Zernov, E.A. Ivanov, T.K. Makhina, V.L. Myshkina, O.V. Samsonova, A.V. Feofanov, A.V. Volkov, J.V. Gazhva, A.A. Muraev, V.M. Ryabova, K.V. Shaitan, S.Y. Ivanov, G.A. Bonartseva, A.P. Bonartsev. Sovremennye tehnologii v medicine Vol. 7 (2015).

DOI: https://doi.org/10.17691/stm2015.7.4.06

[14] A.P. Bonartsev, A.L. Iordanskii, G.A. Bonartseva, G.E. Zaikov, Journal of the Balkan tribological association Vol. 14 (2008), pp.359-395.

[15] R.W. Lenz, R.H Marchessault, Biomacromolecules Vol. 6 (2005), pp.1-8.

[16] M.I. Artsis, A.P. Bonartsev, A.L. Iordanskii, G.A. Bonartseva, G.E. Zaikov, Molecular Crystals and Liquid Crystals Vol. 555 (2012), pp.232-262.

DOI: https://doi.org/10.1080/15421406.2012.635549

[17] R. N. Shirazi, F. Aldabbagh, W. Ronan, A. Erxleben, Y. Rochev, and P. McHugh, J. Mater. Sci. Mater. Med. Vol. 27 (2016), p.154.

[18] X. Song, F. Liu, and S. Yu, Catal. Today Vol. 276 (2016), p.145–149.

[19] I. I. Muhamad, L. K. Joon, and M. A. M. Noor, Malaysian Polym. J. Vol. 1 (2006), p.39–46.

[20] N. Koyama and Y. Doi, Can. J. Microbiol. Vol. 41 Suppl 1 (1995), p.316–322.

[21] C. Kunze, H. E. Bernd, R. Androsch, C. Nischan, T. Freier, S. Kramer, B. Kramp, and K. P. Schmitz, Biomaterials Vol. 27 (2006), p.192–201.

[22] T. Freier, C. Kunze, C. Nischan, S. Kramer, K. Sternberg, M. Sa, U. T. Hopt, and K. P. Schmitz, Biomaterials Vol. 23 (2002), p.2649–2657.

[23] N. D. Miller and D. F. Williams, Biomaterials Vol. 8 (1987), p.129–137.

[24] C. Doyle, E. T. Tanner, and W. Bonfield, Biomaterials Vol. 12 (1991), p.841–847.

[25] Y. Marois, Z. Zhang, M. Vert, X. Deng, R. Lenz, R. Guidoin, Journal of Biomedical Materials Research Vol. 49 (2000), pp.216-224.

[26] V.L. Myshkina, E.A. Ivanov, D.A. Nikolaeva, T.K. Makhina, A.P. Bonartsev, E.V. Filatova, A.O. Ruzhitskii, G.A. Bonartseva, Applied biochemistry and microbiology Vol. 46 (2010), pp.289-296.

DOI: https://doi.org/10.1134/s0003683810030075

[27] A.P. Bonartsev, S.G. Yakovlev, I.I. Zharkova, A.P. Boskhomdzhiev, D.V. Bagrov, V.L. Myshkina, T.K. Makhina, E.P. Kharitonova, O.V. Samsonova, A.V. Feofanov, V.V. Voinova, A.L. Zernov, Yu.M. Efremov, G.A. Bonartseva, K.V. Shaitan, M.P. Kirpichnikov, BMC Biochemistry (2013).

DOI: https://doi.org/10.1186/1471-2091-14-12

[28] A.P. Bonartsev, S.G. Yakovlev, A.P. Boskhomdzhiev, I.I. Zharkova, D.V. Bagrov, V.L. Myshkina, T.K. Mahina, E.P. Charitonova, O.V. Samsonova, A.L. Zernov, V.A. Zhuikov, Yu.M. Efremov, V.V. Voinova, G.A. Bonartseva, K.V. Shaitan, PLoS ONE Vol. 8 (2013).

DOI: https://doi.org/10.1371/journal.pone.0057200

[29] V.L. Myshkina, D.A. Nikolaeva, T.K. Makhina, A.P. Bonartsev, G.A. Bonartseva, Applied biochemistry and microbiology Vol. 44 (2008), pp.482-486.

[30] A.P. Bonartsev, G.A. Bonartseva, V.L. Myshkina, V.V. Voinova, T.K. Mahina, I.I. Zharkova, S.G. Yakovlev, A.L. Zernov, E.V. Ivanova, E.A. Akoulina, E.S. Kuznetsova, V.A. Zhuikov, S.G. Alekseeva, V.V. Podgorskii, I.V. Bessonov, M.N. Kopitsyna, A.S. Morozov, E.Y. Milanovskiy, Z.N. Tyugay, G.S. Bykova, M.P. Kirpichnikov, K.V. Shaitan, Acta Naturae Vol. 8 (2016).

DOI: https://doi.org/10.1080/10826068.2016.1188317

[31] A.P. Bonartsev, A.P. Boskhomodgiev, A.L. Iordanskii, G.A. Bonartseva, A.V. Rebrov, T.K. Makhina, V.L. Myshkina, S.A. Yakovlev, E.A. Filatova, E.A. Ivanov, D.V. Bagrov, G.E. Zaikov, Molecular Crystals and Liquid Crystals Vol. 556 (2012).

DOI: https://doi.org/10.1080/15421406.2012.635982

[32] A.P. Boskhomdzhiev, A.P. Bonartsev, T.K. Makhina, V.L. Myshkina, E.A. Ivanov, D.V. Bagrov, E.V. Filatova, A.L. Iordanskii, G.A. Bonartseva, Biochemistry Supplement Series B: Biomedical Chemistry Vol. 4 (2010), p.177–183.

DOI: https://doi.org/10.1134/s1990750810020083

[33] A.P. Bonartsev, A.P. Boskhomodgiev, V.V. Voinova, T.K. Makhina, V.L. Myshkina, S.A. Yakovlev, I.I. Zharkova, A.L. Zernov, E.A. Filatova, D.V. Bagrov, A.V. Rebrov, G.A. Bonartseva, A.L. Iordanskii, Chemistry and Chemical Technology Vol. 6 (2012).

DOI: https://doi.org/10.1201/b14794-10

[34] V. Zhuikov, А. Bonartsev, D. Bagrov, A. Rusakov, A. Useinov, V. Myshkina, T. Mahina, K. Shaitan, G. Bonartseva. Solid State Phenomena Vol. 258 (2017), pp.354-357.

DOI: https://doi.org/10.4028/www.scientific.net/ssp.258.354

[35] V.A. Zhuikov, A.P. Bonartsev, I.I. Zharkova, G.S. Bykova, N.Y. Taraskin, A.V. Kireynov, M.N. Kopitsyna, D.V. Bagrov, G.A. Bonartseva, K.V. Shaitan. Macromolecular Symposia, Vol. 375 (2017), p.1600189.

DOI: https://doi.org/10.1002/masy.201600189

[36] V.A. Zhuikov, A.P. Bonartsev, D.V. Bagrov, S.G. Yakovlev, V.L. Myshkina, T.K. Makhina, I.V. Bessonov, M.N. Kopitsyna, A.S. Morozov, A.A. Rusakov, A.S. Useinov, K.V. Shaitan, G.A. Bonartseva. Molecular Crystals and Liquid Crystals Vol. 648 (2017).

DOI: https://doi.org/10.1080/15421406.2017.1302580

[37] A. P. Bonartsev, A. P. Boskhomodgiev, A. L. Iordanskii, G. A. Bonartseva, A. V. Rebrov, T. K. Makhina, V. L. Myshkina, S. A. Yakovlev, E. A. Filatova, et al., Mol. Cryst. Liq. Cryst. Vol. 556 (2012), p.288–300.

DOI: https://doi.org/10.1080/15421406.2012.635982

[38] A.L. Iordanskii, A.A. Ol'khov, Yu.N. Pankova, A.P. Bonartsev, G.A. Bonartseva, V.O. Popov, Macromolecular symposia Vol. 223 (2006), pp.108-116.

[39] G.G. Choi, H.W. Kim, Y.H. Rhee, Journal of microbiology Vol. 42 (2004), pp.346-354.

[40] K. Sudesh, H. Abe, Y. Doi, Progress in Polymer Science Vol. 25 (2000), p.1503–1555.

Fetching data from Crossref.
This may take some time to load.