The Effect of Nanostructured Hydroxyapatite Coating on Distraction Osteogenesis

Abstract:

Dogs underwent high-frequency automated tibia lengthening with the Ilizarov apparatus over a 1.8-mm hydroxyapatite-coated intramedullary titanium wire. Daily distraction was 3.0 mm with a fraction of 0.125 mm/h and continued ten days. The regenerate was well vascularized, had zonal structure and was of normal or hyperplastic type to the end of distraction. Osteogenesis was fast and complete. The wire served for both mechanical and biological reinforcement of the bone callus and provided reduction of external fixation time. Mean consolidation time with the apparatus on the limb was 13.83±4.02 days. Overall, external fixation index was 10.5 days/cm and 4.8 days/cm in the consolidation phase.

• Periodical: Key Engineering Materials (Volume 854)
• Pages: 216-222
• DOI: https://doi.org/10.4028/www.scientific.net/KEM.854.216
• Online since: July 2020
• Authors: Natalia A. Kononovich*, Arnold V. Popkov, Elena N. Gorbach, Dmitry A. Popkov
• Keywords: Automated Distractor, Dog, Hydroxyapatite Coating, Intramedullary Implant, Lengthening, Osteogenesis, Tibia

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