Formulation of Chewable Toothtablets Containing Mangosteen Rind Extract and Market Feasibility Study in Capital District of Nakhon Pathom Province

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The objective of this research aimed to 1. formulate chewable toothpaste tablets containing mangosteen rind extract, 2. compare the suitable filler between lactose anhydrous and mannitol that adsorbs mangosteen rind extract by flowability and appearance indicators, 3. study the effect of type and amounts of foaming agents on stability of foam that leads to appropriate formulation, and 4. study market feasibility of chewable toothpaste tablets containing mangosteen rind extract. Survey method and self-administered questionnaire was used for data collection both before and after formulation in capital district of Nakhon Pathom. Thirty participants were selected and categorized into five groups which are tourists, dental patients, pharmacy students at Silpakorn University, office workers and dentists. After data collection is done, it was analyzed by using descriptive statistics. Results showed that mannitol is an appropriate adsorbent. It showed proper color and appearance as well as good flowability of extract. Cocamidopropyl betaine was selected as foaming agent. According to the survey, participants are interested in product. In addition, some dental specialists suggested to add fluoride. Overall, this product is interested and accepted among participants. Therefore, consumers are likely to buy chewable toothpaste tablet containing mangosteen rind extract.

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28-34

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October 2021

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