Synthesis of Novel Trimethoprim Complexes and Their Analysis by Ultraviolet Derivative Spectroscopy

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Abstract:

In this research, the actions of antibiotic trimethoprim alone and with metals combained. Then assayed through formation of base transition metal compounds as ligands have the chance to achieve an unusual arrangement and stability complexes of coordination. We show advancement in using transtional metal compounds medications for treamentt manyl human illnesses such as carcinomas, lymphomas, control of infections, anti-inflammatory disorders, diabetes, with neurological conditions. This combination with transition metal observed the interaction can be separated by derivative spectroscopic method and measure the characterization of compound by IR and UV spectroscopy.

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Materials Science Forum (Volume 1021)

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200-209

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February 2021

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© 2021 Trans Tech Publications Ltd. All Rights Reserved

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[1] M. Shamsipur, A.R. Ghiasvand, Solid phase extraction of ultra tracecopper(II) using octadecyl silica membrane disks modified by a naphthol derivative schiff's base, Anal ChimActa. 408 (2000) 271-277.

DOI: 10.1016/s0003-2670(99)00873-9

Google Scholar

[2] K.K. Reddy, R. Sayaji, S. R. Biyyala, Synthesis and characterization and biological activities of hydrazones, Int J Innovative Res SciEngTechnol. 4 (2005) 18944-18952.

Google Scholar

[3] E.S. Jose, R.S. Edward, E.T.G. Cavalheirob, Synthesis and characterization of Schiff bases from chitosan and salicylaldehyde derivatives. Carbo. Poly. 60 (2005) 277-282.

Google Scholar

[4] Trimethoprim,, The American Society of Health-System Pharmacists. Archived from the original on (2015) 09-24.

Google Scholar

[5] A. Hoffmann, J. Borner, U. Florke, S. H. Pawlis, Synthesis and Properties of guanidine-pyridine hybrid ligands and structural characterization of their mono – and bis (chelated) Cobalt complexes, Inorganica Chimica Acta. 362 (2009) 1185-1193.

DOI: 10.1016/j.ica.2008.06.002

Google Scholar

[6] A. Ahmed, D. Mahmood and F. Hammed, Preparation and Spectral Characterization of Isonazide Ligand with Some TransitionMetal Complexes, Aust. J. Basic Appl. Sci. 9 (2015) 42-46.

Google Scholar

[7] F. M. Ibrahim, R. A. Hammza, D. H. Fadhel, synthesis and characterization of trimethoprim metal complexes used as corrosion inhibitors for carbon steel in acidic media, inhib. 3 (2019) 733-742.

DOI: 10.17675/2305-6894-2019-8-3-20

Google Scholar

[8] D. Coutinho, J. Costa, J. Lima, G. EO, Enhancement of the antibiotic activity against a multiresistant Escherichia coli by Menthaarvensis L. and chlorpromazine, Chemother. 54 (2008) 328–330.

DOI: 10.1159/000151267

Google Scholar

[9] R. Alsayed, H. Adil, A. Al-Hussin, Z. Hussain, S. Mohammed, E. Yousif, Antioxidant activity of vitamins against free radicals, Inter. J. Res. Eng. & Innov. 2 (2018) 249-252.

Google Scholar

[10] A. Ahmed, D. Mahmood, F. Hameed, Preparation and Spectral Characterization of Isonazide Ligand with Some Transition Metal Complexes, Aust. J. Basic Appl. Sci. 9 (2015) 42-46.

Google Scholar