Biocompatibility of Carbon Layer on Polymer

Abstract:

Polymers with modified surface structure are useful for medicine applications. This study is focused on the surface properties of polymers with carbon layers and their biocompatibility. For experiments was used polyethyleneterephtalate (PET). We used magnetron sputtering for producing of the carbon layers. Raman spectroscopy, goniometry, AFM – microscopy, X-ray diffraction and infrared spectroscopy were used in our experiments to describe the physicochemical properties of modified polymers. Biocompatibility of structure polymer-carbon layers was studied with method in vitro. We investigated adhesion of mouse 3T3-fibroblasts. The carbon layers have positive influence on biocompatibility.

• Periodical: Materials Science Forum (Volume 482)
• Pages: 247-250
• DOI: https://doi.org/10.4028/www.scientific.net/MSF.482.247
• Online since: April 2005
• Authors: O. Kubová, Lucie Bačáková, Václav Švorčík
• Keywords: 3T3 Fibroblasts, Biocompatibility, Carbon Layer, Polymer

References

[1] M.A. Thornton, L.C. Howard and E.A. Patternson: Med. Eng. Phys. Vol. 19 (1997), p.588.

[2] L. Bačáková, V. Mareš, M.G. Bottone, C. Pellicciari, V. Lisá and V. Švorčík: J. Biomed. Mater. Res. Vol. 49 (2000), p.369.

[3] K. Smetana, B. Dvořánková, J. Jelínková, J. Michálek and J. Vacík: J. Mater. Sci. Mater. Med. Vol. 8 (1997), p.587.

[4] G. Lewis: J. Biomed. Mater. Res. Vol. 38 (1997), p.55.

[5] R. Brooks, E. Jones, A. Stoper and N. Rushton: Biomaterials Vol. 25 (2003), p.3429.

[6] J. Wang, N. Huang, P. Yang, Y. Leng, H. Sun, Z. Liu and P. Chu: Biomaterials Vol. 25 (2004), p.3163.