CdSe/ZnS Quantum Dots Loaded Solid Lipid Nanoparticles: Novel Luminescent Nanocomposite Particles

Abstract:

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Highly luminescent lipophilic CdSe/ZnS core-shell QDs with an emission maximum at 556 nm were synthesized. These QDs were successfully encapsulated into solid lipid nanoparticles (SLNs) using the thin-layer ultrasonication technique. Transmission electron microscopy (TEM), photon correlation spectroscopy (PCS), and zeta potential measurement were employed to characterize the QDs-loaded SLNs for morphology, particle size with polydispersity index (PI), and zeta potential. The nanocomposite particles obtained appeared in a shape of spherical or near spherical with the average size of 92.3 nm, PI of 0.235 and zeta potential of -28.74 mV. Each nanocomposite particle contains tens of QDs observed by TEM. Fluorescence measurements show that the encapsulated QDs maintain their high luminescence and narrow/symmetric emission spectra. The experiment result indicates that the nanocomposite particles are stable and slow to photobleach. These luminescent nanocomposite particles have good potentials in biological imaging applications.

Info:

Periodical:

Materials Science Forum (Volumes 510-511)

Edited by:

Hyung Sun Kim, Yu Bao Li and Soo Wohn Lee

Pages:

170-173

DOI:

10.4028/www.scientific.net/MSF.510-511.170

Citation:

W. Liu et al., "CdSe/ZnS Quantum Dots Loaded Solid Lipid Nanoparticles: Novel Luminescent Nanocomposite Particles", Materials Science Forum, Vols. 510-511, pp. 170-173, 2006

Online since:

March 2006

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Price:

$35.00

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