Synthesis and Characterization of Chitosan/Hydroxyapatite Biocomposites Obtained by Reaction of Precipitation

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Abstract:

There is a growing need for new biomaterials that can gain predictable and controlled tissue response, this is, that as bone graft substitutes should initiate new bone formation, after which they should get reabsorbed and replaced by bone tissue. This combination aims to improve the mechanical properties, degradation rates and absorption rates of biocompatibility and biodegradability. The aim of this study was to propose a synthetic route in which the HA was obtained by reaction of precipitation directly on evaluating the influence of chitosan biopolymer in the middle of precipitation in the characteristics of hydroxyapatite obtained. XRD analysis revealed the presence of HA phase with low crystallinity. In the FTIR analysis identified the characteristic bands of hydroxyapatite, as well as bands that characterize an interaction between chitosan and hydroxyapatite, as the band around 1050cm-1. SEM analysis of the biocomposites chitosan/HA, showed a dispersion of HA particles in chitosan, revealing a homogenous material and microporous.

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Materials Science Forum (Volumes 727-728)

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614-618

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August 2012

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© 2012 Trans Tech Publications Ltd. All Rights Reserved

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[1] A. Uchida, N. Araki, Y. Shinto, H. Yoshikawa, E. Kurosaki and K. Ono: J. Bone Joint Surg. Vol. 72B (1990), p.298.

Google Scholar

[2] M. Bohner: Injury Vol. 31 (2000), p.37.

Google Scholar

[3] L.A. Santos: Desenvolvimento de Cimento de Fosfato de Cálcio Reforçado por Fibras para uso na Área Médico-Odontologica. Doutorado (Tese). Campinas, 2002. Universidade Estadual de Campinas (UNICAMP/FEM). (SP).

DOI: 10.47749/t/unicamp.2002.226008

Google Scholar

[4] T. Volkmer: Obtenção e Ccaracterização de Hidroxiapatita Porosa pelo Método Gelcasting de Espumas para uso como Implantes. Mestrado (Dissertação). Porto Alegre, 2006. Universidade Federal do Rio Grande do Sul (UFRGS/MMMater). (RS).

DOI: 10.32467/issn.2175-3628v23n1a14

Google Scholar

[5] L.C. Angelo: Síntese e Caracterização de nanocompósitoshidroxiapatita-gelatina obtidos pelo método de precipitacao utilizando o método de Rietveld e Ivtf. Mestrado (Dissertação). Ponta Grossa, 2008. Universidade Estadual de Ponta Grossa (UEPG). (PR).

DOI: 10.5212/terraplural.v.15.2119754.036

Google Scholar

[6] T.H.S. Souza, C.A. Fortulan, E.S. Antunes and B.M. Purqueiro: 17° Congresso Brasileiro de Ciência dos Materiais (CBECIMAT). Foz do Iguaçu 15-19 de Novembro 2006. Procceding.. Foz do Iguaçu 2006. (PR).

DOI: 10.5752/p.2318-2962.2019v29n57p561-582

Google Scholar

[7] K.A. Almeida: Sistema Hibrido Macroporoso para Enxertos Ósseos Aloplásticos. Mestrado (Dissertação). Itajubá, 2003. Universidade Federal de Itajubá (UNIFEI). (MG).

Google Scholar

[8] M.C.M. Laranjeira and V. Fávere: Química Nova Vol. 32 (2009), p.672.

Google Scholar

[9] K.M.N.C. Canella and R.B. Garcia: Química Nova Vol. 24 (1) (2001), p.13.

Google Scholar

[10] O.B.G. Assis and V.L. Silva: Polímeros: Ciência e Tecnologia Vol. 13 (4) (2003), p.223.

Google Scholar

[11] J.Y. Lee et al.: J. Control Release Vol. 78 (1/3) (2002), p.187.

Google Scholar

[12] S. Senel, S.J. McClure: Adv. DrugDeliv. Rev. Vol. 56 (10), (2004), p.1467.

Google Scholar

[13] C. Damian, L.H. Beirão, A. Francisco, M.L.P. Espirito Santo and E. Teixeira: Alim. Nutr. Vol. 16 (2) (2005), p.195.

Google Scholar

[14] M. Ito: Biomaterials Vol. 12 (1991), p.41.

Google Scholar

[15] M.R. Finisie, J. Atche, V.T. Fávere and M.C.M. Laranjeira: Synthesis of Calcium-Phosphate and Chitosan Bioceramics for Bone Regeneration, (2000).

DOI: 10.1590/s0001-37652001000400006

Google Scholar

[16] A.C.M. B Fook: Desenvolvimento de Biocerâmicas Porosas Para Regeneração Óssea. Mestrado (Dissertação). Campina Grande, 2007. Universidade Federal de Campina Grande (UFCG). PB.

DOI: 10.24873/j.rpemd.2021.10.846

Google Scholar

[17] L. Jiang, Y. Li, X. Wang, L. Zhang, J. Wen and M. Gong: Carbohydrate Polymers Vol. 74 (2008), p.680.

Google Scholar

[18] I. Manjubala, S. Scheler, J. Bossert, and K.D. Jandt: Acta Biomaterialia Vol. 2 (2006), p.75.

Google Scholar