A Novel Method for the Synthesis of Amphiphilic Copolymer: PHEMA-b-PDMS-b-PHEMA

Abstract:

In this study, a novel amphiphilic copolymer based on the flexible polydimethylsiloxane (PDMS) macroinitiator was successfully prepared by atom transfer radical polymerization (ATRP). First, the high molecular weight bis (hydroxyalkyl)-terminated PDMS was prepared by hydrosilation reaction between hydrogen-terminated PDMS and 2-allyloxyethanol in the presence of Karstedt’s catalyst. The macroinitiator Br-PDMS-Br was prepared by the reaction between different molecular weight bis (hydroxyalkyl)-terminated PDMS and 2-bromoisobutyry bromide. Then the amphiphilic ABA-type block copolymers of poly [dimethylsiloxane-b-(hydroxylethyl methacrylate)] were initiated by bromide end-capped PDMS with HEMA, under an appropriate catalyst/ligand system of CuCl/bpy. The polymerization proceeded with first-order kinetics. It showed that the reaction system was a controlled/‘living’ polymerization. The triblock copolymers were characterized by FTIR, ¹H-NMR, TGA and GPC techniques. GPC results showed the tribolck copolymer had narrow polydispersity of Mw/Mn (PDI<1.5). TGA results showed the good thermal stability of the triblock copolymer.

• Periodical: Materials Science Forum (Volume 789)
• Pages: 230-234
• DOI: https://doi.org/10.4028/www.scientific.net/MSF.789.230
• Online since: April 2014
• Authors: Jian Feng Xu, Xiao Quan Peng, Chun Ju He
• Keywords: Amphiphilic, ATRP, Hydrosilation, Triblock Copolymer

References

[1] J. Xia, K. Matyjaszewski, Atom transfer radical polymerization, Chem. Rev. 101 (2001) 2921-2990.

DOI: 10.1021/cr940534g

[2] N.K. Singha, B. de Ruiter, U.S. Schubert, Atom transfer radical polymerization of 3-​ethyl-​3-​(acryloyloxy)​methyloxetane , Macromolecules. 38(2005) 3596-3600.

DOI: 10.1021/ma0401119

[3] A. Ramakrishnan, R. Dhamodharan, Facile synthesis of ABC and CBABC multiblock copolymers of styrene, tert​-butyl acrylate, and methyl methacrylate via room temperature ATRP of MMA, Macromolecules. 35(2003) 1039-1046.

DOI: 10.1021/ma021197d

[4] S. K. Jewrajka, U. Chatterjee, B.M. Mandal, Homogeneous atom transfer radical polymerization of methyl methacrylate at ambient temperature in aqueous ethanol, Macromolecules. 37(2004) 4325-4328.

DOI: 10.1021/ma0497613

[5] S. Lahooti and M. V. Sefton, Microencapsulation of normal and transfected L929 fibroblasts in a HEMA-​MMA copolymer,Tissue Eng. 6(2000),139-149.

DOI: 10.1089/107632700320766

[6] M.D.P. Wilcox, N. Harmis, B. A. Cowell, T. Williams and B. A. Holden, Bacterialinteractions with contact lenses; effects of lens material, lens wear and microbial physiology, Biomaterials. 22(2001) 3235-3247.

DOI: 10.1016/s0142-9612(01)00161-2

[7] A. Sheena, B. Sean, I. Kazuhiko, G.E. Anthony, Molecularly engineered p(HEMA)​-​based hydrogels for implant biochip biocompatibility, Biomaterials. 26(2005) 4767- 4768.

DOI: 10.1016/j.biomaterials.2005.01.031