Analysis on Fluid Characteristics in Y-Shape Bifurcate Coronary Artery

Abstract:

This article analyzes the bifucate Y-type coronary artery based on hemodynamics and computational fluid dynamics to study the optimal location for thrombosis. Mathematical derivation is used to analyze the fluid machanics. The issue of fully developed flow is derivated. The optimal location for thrombus is identified. According to the mathematical derivation and numerical modeling results, the optimal location for thrombus is at the bifurcation of coronary artery. Vortex and turbulent fluctuation will take place. Three bifurcate angle (60, 90 and 120) is chosen to analyze by numarical stimulation. The result shows that vortex at bifurcation area grows when the bifrucate angle increases. It may cause the sediment of blood platelet, fibrous protein and lipochondrion [1]. It is also concluded that the wall shear stress is so high that it may injure the vascular wall around bifurcation.

• Periodical: Materials Science Forum (Volume 857)
• Pages: 452-458
• DOI: https://doi.org/10.4028/www.scientific.net/MSF.857.452
• Online since: May 2016
• Authors: Ye Lu, Shusheng Zhang
• Keywords: Computational Fluid Dynamics, Hemodynamics, Y-Shape Coronary Artery

References

[1] Mei Liquan, Zhao Ke: The influence of arterial stenosis in bifurcate blood vessel on the blood flow[J]. Chinese Journal of Applied mechanics. 2013 Vol. 30 N0. 3, P. 417.

[2] Charles. A. Taylor, Thomas. J. R a1. Finite element modeling of blood flow in arteries Computer Methods in Applied Mechanics and Engineering. 1998 P. 156·196.

[3] El. Menyaraa, Al. Suwaidi. Jassimtmain, et al. Left main coronary artery stenosis: State-of-the-art [J]. Curr Probl Cardiol, 2007, Vol. 32: 103-193.

DOI: 10.1016/j.cpcardiol.2006.12.002

[4] Sianos. G, Papafaklis. M. I, Daemen. J, et al. Angiographic sent thrombosis after routine use of Drug-Eluting sents in ST-segment elevation myocardial Infarction [J]. Journal of American College of Cardiology, 2007, Vol. 50 No. 7: 573-583.

DOI: 10.1016/j.jacc.2007.04.059

[5] Grube E, Buellesfeld L, et al. Six-month clinical and angiographic results of a dedicated drug-eluting stent for the treatment of coronary bifurcation narrowing [J]. The American Journal of Cardiology, 2007, Vol. 99: 1691-1697.

DOI: 10.1016/j.amjcard.2007.01.043

[6] Hoye. A, Iakovou. I, et al. Long-term outcomes after stenting of bifurcation lesions with the Crush, technique—Predictor of an adverse outcome [J]. Journal of the American College of Cardiology, 2006, Vol. 47 No. 10: 1949-(1958).

DOI: 10.1016/j.jacc.2005.11.083

[7] Politis. A. K, Stavropoulos G. P, et al. Numerical modeling of simulated blood flow in idealized composite arterial coronary grafts: Steady state simulations [J]. Journal of Biomechanics, 2007, Vol. 40: 1125-1136.

DOI: 10.1016/j.jbiomech.2006.05.008

[8] Jafari. A, Mousavi. S. M, KolariP. Numerical investigation of blood flow. Part I: In micro vessel bifurcations [J]. Communications in Nonlinear Science and Numerical Simulation, 2008, Vol. 13: 1615-1626.

DOI: 10.1016/j.cnsns.2006.09.017

[9] O.C. Benolotti, V. Deplano. Three-Dimensional Numerical Simulations of flow through a Stenosed Coronary Bypass., journal of biomechanics. 2001, Vol. 34: 1049-1064.

DOI: 10.1016/s0021-9290(00)00012-9

[10] Quarteroni. A. Computational vascular fluid dynamics: problems, models and methods [J]. Computing and Visualization in Science, 2000, Vol. 2: 163-197.

DOI: 10.1007/s007910050039

[11] Liu Zhaomiao, Ma Ruiyan et al. Influence of blood flow on thrombosis in Y-shape coronary arteries. Journal of Beijing University of Technology. 2010. Vol. 36 No. 9: 1153-1158.

[12] Peng Hongmei, Yang Dequan. the boundary element analysis on Y-bifurcation arterial hemodynamic characteristics. Chinese Journal of Medical Physics. 2011 Vol. 28 No. 5: 2937-2940.

[13] Zhang Xujing, Huang Jiuyi et al. Hemodynamics and atherosclerosis. International Journal of Cerebrovascular Disease. 2006. Vol. 14 No. 3: 228-230.