Radiation Effect on Poly(ε-Caprolactone) Nanofibrous Scaffold

Abstract:

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Nano- to micro-structured biodegradable poly(ε-caprolactone) nanofibrous scaffolds (PCL NFSs) were prepared by an electrospinning. Electrospinning has recently emerged as a leading technique for generating the biomimetic scaffolds for tissue engineering applications. The average diameter of the electrospun PCL NFSs ranged from 0.5 to 2 ㎛ depending on the solvent/nonsolvent mixture. PCL NFSs were irradiated using γ-ray and their mechanical properties and biodegradability were measured. In vitro/vivo degradation studies of the scaffolds as a function of the radiation dose were performed. The scaffolds were degraded more slowly in vitro than in vivo.

Info:

Periodical:

Solid State Phenomena (Volume 119)

Edited by:

Chang Kyu Rhee

Pages:

95-98

DOI:

10.4028/www.scientific.net/SSP.119.95

Citation:

Y. M. Lim et al., "Radiation Effect on Poly(ε-Caprolactone) Nanofibrous Scaffold", Solid State Phenomena, Vol. 119, pp. 95-98, 2007

Online since:

January 2007

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Price:

$35.00

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