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A Novel Thermosensitive Composite Fabricated with Au Nanoparticles, Poly(Lactide), and Poly(N-Isopropylacrylamide)
Abstract:
A novel approach to load a hydrophilic bovine serum albumin (BSA) into the drug carriers was proposed in terms of thermosensitive dual-shell structures which were fabricated with poly(N-isopropylacrylamide), poly(lactide) and Au nanoparticles. Spherically well-defined dualshell structures were constructed by a modified-double-emulsion method (MDEM). The lower critical solubility temperature of the structures was shifted to 36.4 °C which was confirmed by UVVis spectroscopy.
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161-164
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July 2004
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© 2004 Trans Tech Publications Ltd. All Rights Reserved
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