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The Specific Binding between Aptamer and Its Target Molecules Investigated by Microcantilever Sensor Huiyong Zhang Department of Materials Science and Engineering, Luoyang Institute of Science and Technology, Luoyang, 471023, China zhanghuiyong187@163.com Keywords: Cantilever; PDGF-BB; Cocaine Abstract.
Experiment Materials and Reagents.
Rectangular silicon microcantilever (length 350μm, width 35μm, thickness 1μm, elastic constant of 0.03 N/m, one side of the microcantilever surface was coated by 10-nm chromium adhesion layer and followed by plating 50 nm gold) was purchased from NT-MDT company; Platelet-derived growth factor-BB (PDGF-BB) from human was purchased from Sigma-Aldrich Company; cocaine hydrochloride reference substance was bought from the National Institute of Control of Pharmaceutical and Biological Products; mercapto-modified PDGF-BB aptamer (5'-HS-(CH2)6-CAGGCTACGGCACGTAGAGCATCACCATGATCCTG) and thiol-modified cocaine aptamer (HS-(CH2) 6 - 5'-AG ACAA GGA AAATCCTTCAAT-GAAGTGG GTC G-3') were synthesized by Shanghai Biological Engineering Company; Tris-HCl, NaCl and MgCl2 (analytical grade) were purchased Since Sinopharm Chemical Reagent Co., Ltd. in Shanghai.
Stacking interaction plays a key role in most nucleic acid / ligand complex, especially in aptamer / protein complexes, followed by hydrogen bonding and other interactions.

Consequently, R peaks detection, under different acquisition conditions, continues to be an attractive domain of research in biomedical engineering.
In Section 2, the materials and methods are expressed in details.
Materials and Methods 2.1 Mathematical background In this section the used mathematical tools to improve the original works described in [8, 16, 17] are presented: 2.1.1 Fast Fourier Transform (FFT) The fast Fourier transform (FFT) is one of the most useful tool and it is widely and intensively used in many recent research as in [18, 19].
It is defined as follow: Let x(n) be a time sequence with N samples (n = 0, 1, …, N − 1) , the discrete Fourier transform (DFT) of x(n) is expressed by the following equation: X(k) = N−1X n=0 x(n)wnkN (1) Where: wN = e− j2π N However, the most used Fourier transform is its rapid version well-known as the Fast Fourier Transform (FFT) [20].2.1.2 Scaling using FFT and IFFT The key idea of the scaling using FFT is that a signal of length N can be down-sampled or up-sampled depending on the chosen value of the scaling factor α to obtain a new signal of length N0 = αN [21].
Suresh, Signals and Systems in Biomedical Engineering, Springer-Verlag, New York, 2012.

On the basis of blending a scientific and rational city development planning, it uses a variety of engineering and technical measures of comprehensive management of the coal mining subsidence area and makes the city an ecological system integration, thus effectively improving the city ecosystem robustness.
According to the global ecological management mode and by using the engineering and technology measures for the management of project area, in 2008 on a large-scale expansion of the lake and the green land, it took only more than 1 year to complete the basic park management and reform.
Table 2 Table of estimation of the ecological and economic benefits about city ecological park Function Biological habital Climatic regulation Pollution reducing and purification Leisure tourism Scientific research education Material production Total benefits million yuan /a 1195.05 15.84 1083.47 182.5 255.75 7511.78 10244.4 Proportion/% 11.67 0.15 10.58 1.78 2.5 73.33 100 Note: the total benefit of coal production efficiency 70.28% Table 2, shows that the city ecological park total economic benefits are RMB￥102.444 million, but the coal production accounts for 70.28% of the total benefits.
Main wet plants are Phragm ites australis and Typha angustata Bory et Chaub with strong water absorption capability, which can effectively regulate the air humidity, and absorb water in the contaminated materials, so as to achieve the purpose of purifying the water quality.
In order to evaluate the quality of water environment treatment, a few key factors are selected, including CODcr, BOD5, NH3-N, TP,DO and other nine indicators [9]; the results shows the above indexes exceeded bid badly and the water was severely polluted.

Research on Environmental Risk Assessment of Contaminated Sites Reuse Liwei Sheng1, a, Yuzhao Feng1,b*, Haibo Yu2,a, Rongji Sun2,b,Pengfei Li3,a, Heng Zhang3,b 1,2,3 Dept. of Military Architecture & Planning & Environmental Engineering, LEU, Chongqing , China 1,a liweis_leu@126.com, 1,b1297345332@qq.com Key words: contaminated sites; routes of harms; health risk assessment; uncertainty; legislation Abstract.
Among 323 769 large-scale industrial enterprises (20 million Yuan or more annual sales revenue), nearly 10.94% are high polluting enterprises, including petrochemical, metallurgical, chemical raw materials and chemical products manufacturing, pharmaceutical manufacturing, metal, black metal and non-ferrous metal smelting and rolling processing, electronic equipment manufacturing and so on [7].
The qualitative and quantitative evaluation for material toxicity, merely considering the impact on human health under different exposure levels, toxicity assessment includes the hazard determination and the dose - response evaluation.
Transactions of the Chinese Society of Agricultural Engineering, 2013, 12:228-234.
Journal of environmental engineering, 2003 practices: + 5 to 6, 66-69.

Heat Transfer Approach to Modelling and Analysis of Reverse logistics Inventory Models Nasim Nahavandi1, Farzad Haghighi Rad2 and Saeed Farokhi3 1Assistant Professor, Faculty of Engineering, Tarbiat Modares University, Tehran, IRAN P.O.
Box: 14115-179 2PhD student, Faculty of Engineering, Tarbiat Modares University 3Ms student, Faculty of Mechanical Engineering, University of Tehran 1Tel: +98(21)82883961; Email: 1n_nahavandi@modares.ac.ir, 2haghighirad@yahoo.com, 3saeedfa@gmail.com Key words: reverse logistics, inventory model, heat transfer, return of products Abstract.
Reverse logistics (RL) is defined as: the process of planning, implementing and controlling the efficient, cost-effective flow of raw materials, in process inventory, finished goods and related information from the point of consumption to the point of origin for the purpose of recapturing or creating value or for proper disposal [14].
Computers & Industrial Engineering, vol. 58, 2010, pp. 352-362
Computers & Industrial Engineering, vol. 43, 2002, pp. 59-73

Mehedi Hasan, Rajib Al Mamun, Ruhul Amin Khan (2019), Comparative Study of Jute, E-glass and Carbon Kevlar Fabric Reinforced Polypropylene Composite, Chemical and Materials Engineering 7(1), 1-8
Khan (2019), Natural fiber reinforced polymer composites: history, types, advantages, and applications, Materials Engineering Research, 1(2), 69-87
A Review on Mechanical Properties of Natural Fiber Reinforced Hybrid Polymer Composites, Journal of Minerals and Materials Characterization and Engineering, 3, 420-426
Ershad Khan and Sheikh Nazmul Hoque (2018), Fabrication, Mechanical Characterization and Interfacial Properties of Okra Fiber Reinforced Polypropylene Composites, International Journal of Engineering Materials and Manufacture, 3(1) 18-31
Materials & Design, 27 (5), 391-396

Introduction Detecting damage in a structure by monitoring has been an important task throughout the literature devoted to aerospace, mechanical and civil engineering.
A physical parameter as the plate thickness or the material properties of an specific element can be chosen as updating variable, therefore, the engineer can analyze easily the credibility of the results.
The key point is that the analysis set does not include the clamped nodes.

Frist-Principles Study of Hydrogen Atom Diffusion on Transition Metal doped Mg(0001) Surface Zhi-wen Wang1,a, Xin-jun Guo1,b, Wei Yuan1,c, Zhi-yan Ding1,d 1Department of Materials Engineering, Xinxiang Polytechnic College, Xinxiang 453006, China awangfei331331@163.com,bhanjiebu@126.com,cyuanwei197500@163.com, d15836166302@163.com Keywords: First-principles, Density functional theory, Mg films, Transition metals, Diffusion barrier , Abstract.
Magnesium is regarded as a possible hydrogen storage material due to its high hydrogen storage capacity (magnesium hydride corresponds to 7.6 wt.% hydrogen) and low cost. [5,6,7].
However, One key blockade to prevent Mg from practical application in hydrogen storage is its slow hydrogenation kinetics and high dehydrogenation temperature [8].
Contrasting with Ti doping, a Pd dopant will result in a very small activation barrier for dissociation of molecular hydrogen diffusion of atomic H on the Mg surface. the computational finding supports the proposed hydrogen spillover mechanism for rationalizing experimentally observed fast hydrogenation kinetics for Pd-capped Mg materials.
Hydrogen sorption in mechanically alloyed nanocrystalline and disordered materials.

Kanomata4, e 1Department of Materials Science, Tohoku University, Sendai 980-8579, Japan 2Institute for Materials Research, Tohoku University, Sendai 980-8577, Japan 3National University of Science and Technology “MISiS”, Moscow 119049, Russia 4Faculty of Engineering, Tohoku Gakuin University, Tagajo 985-8537, Japan.
akainuma@material.tohoku.ac.jp, bw-ito@material.tohoku.ac.jp, crieume@imr.tohoku.ac.jp, dkhovaylo@misis.ru, ekanomata@tjcc.tohoku-gakuin.ac.jp Key words: metamagnetic shape memory, metamagnetic phase transition, martensitic transformation, magnetic field-induced strain, layered structure, magnetic property, Ni-Mn-In, Ni-Mn-Sn Abstract.
Introduction Shape memory alloys (SMAs) with applications in various fields, such as medical guidewires, cellar-phones antennas, and smart actuators, are also potential candidates for actuators such as motors and supersonic oscillators, because of the extremely large strain and stress generated by the shape memory effect (SME) as compared to those generated in piezoelectric and magnetostrictive materials.

Electromechanical Resonance in Magnetoelectric Composites: Direct and Inverse Effect Mirza Bichurin1, a, Vladimir Petrov1, b, Roman Petrov1, c and Shashank Priya2, d 1Institute of Electronic and Information Systems, Novgorod State University, Veliky Novgorod, 173003, Russia 2Materials Science and Engineering, Virginia Tech, Blacksburg, VA 24061, USA amirza.bichurin@novsu.ru, bvladimir.petrov@novsu.ru, cinitra@yandex.ru, dspriya@vt.edu Keywords: Multiferroic, direct and inverse magnetoelectric effect, electromechanical resonance.
The thorough investigation of ME materials is stipulated by potential application for novel devices.
The ME voltage coefficients is estimated from the known material parameters.
Bear in mind, that in reality, there are always loss factors that must be included, even in “perfect” materials if for no other reason than losses associated with electrical contacts.
Calculations were performed using the following values of the materials parameters: for NFO ms11 = 6.5·10-12 m2/м, ms12 = -2.4·10-12 m2/м, mq31 = 70·10-12 м/A, mq11 = -430·10-12 м/A, mq12 = 125·10-12 м/A, mε33/ε0 = 10; and for PZT ps11 = 15.3·10-12 m2/м, ps12 = 5·10-12 m2/м, pd31 = -175·10-12 м/В, pε33/ε0 = 1750.