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Characterization of Hydrophilized PCL Electrospun Sheet as an Efective Guided Bone Regeneration Membrane

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Abstract:

Electrospinning is a fabrication process that can produce highly porous nano-scale fiber-based matrices using an electrostatically driven jet of polymer solution. This method represents an attractive approach for polymeric biomaterial processing which provides the membrane structure that may retain mechanical strengths, flexibility, and high surface area. In this study, we prepared a guided bone regeneration (GBR) membrane with selective permeability, hydrophilicity, good mechanical strength and adhesiveness with bone using polycaprolactone (PCL) and Tween 80 by the electrospinning method. The prepared PCL and PCL/Tween 80 electrospun sheets were characterized via morphology observation, mechanical property, water absorbability, and model nutrient permeability. It was observed that the PCL/Tween 80 (3 wt%) electrospun sheet have an effective permeation of nutrients as well as the good mechanical strength to maintain a secluded space for the bone regeneration. From the results, the hydrophilized PCL/Tween 80 (3 wt%) electrospun sheet seem to be a good candidate as a GBR membrane.

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Periodical:

Key Engineering Materials (Volumes 342-343)

Pages:

293-296

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.342-343.293

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Online since:

July 2007

Authors:

Wan Jin Cho, Jun Ho Kim, Se Heang Oh, Jin Ho Lee

Keywords:

Electrospun, Guide Bone Regeneration Membrane, Nanofiber, Polycaprolactone, Selective Permeability, Tween 80

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© 2007 Trans Tech Publications Ltd. All Rights Reserved

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References

[1] P.K. Baumgarten: J. Colloid. Interf. Sci. Vol. 36 (1971), p.71.

Google Scholar

[2] L. Larronda and R.S.J. Manley: J. Polym. Sci. Vol. 19 (1981), p.909.

Google Scholar

[3] Formhals, U.S. Patent 1, 975, 504 (1934).

Google Scholar

[4] Z.M. Huang, Y.Z. Zhang and M. Kotaki: Compos. Sci. Technol. Vol. 63 (2003), p.2223.

Google Scholar

[5] A. Piattelli, A. Scarano and M. Paolantoni: Biomaterials Vol. 17 (1996), p.1725.

Google Scholar

[6] A.V. Imbronito and J.H. Todescan: Biomaterials Vol. 23 (2002), p.4079.

Google Scholar

[7] G . Hillmanan, A. Steinkamp-Zucht and W. Geursen: Biomaterials Vol. 23 (2002), p.1461.

Google Scholar

[8] H. Maeda and T. Kasuga: Biomaterials Vol. 27 (2006), p.1216.

Google Scholar

[9] Annual Book of ASTM Standard, ASTM D638, Vol 08. 01 (1996).

Google Scholar

[10] S.H. Tan, R. Inai and M. Kotaki: Polymer Vol. 46 (2005), p.6128.

Google Scholar

[11] K. Fujihara, M. Kotaki and S. Ramakrishna: Biomaterials Vol. 26 (2005).

Google Scholar