Dynamic responses of flexi rotor-ball-bearing system under unbalance misalignment rubbing coupling faults are studied. Coupling faults dynamic control model of flexi-multi-system of rotor-ball-bearing system is established, based on finite element analysis and numerical integral combined simulate method. Then nonlinear bearing force and rub-impact force models are programmed in MATLAB. Analysis and compare vibration characteristics of system while under faults-free, unbalance and rub-impact faults. The result demonstrates that when system under unbalance faults, vibration frequency brought by eccentric mass is agreed with rotating speed frequency, its fundamental frequency wave add high frequency component, can show the characteristics of unbalance-rubbing faults efficiently; when system under misalignment faults, with frequency double vibration and high harmonics; when system under unbalance-misalignment-rubbing coupling faults, support force of shafting of rotor system appears high frequency responses like saw tooth based on sine wave, causing aggravation of rub-impact faults.