Antitumor Activities of Hydroxylated 9,10-Anthraquinone Derivatives
A series of novel Hydroxylated 9,10-anthraquinone derivatives were designed and synthesized as potential antitumor agents starting from the natural product Emodin. The structures of the compounds were identified by NMR, ESI-MS and elemental analysis. Their antitumor activities against KLE cell line were tested by MTT assay. Some of them were found to exhibit a cytotoxicity profile more potent than Emodin on KLE cell line.
X. P. Wang and W. F. Xu, "Antitumor Activities of Hydroxylated 9,10-Anthraquinone Derivatives", Applied Mechanics and Materials, Vol. 108, pp. 294-296, 2012