Antitumor Activities of Hydroxylated 9,10-Anthraquinone Derivatives

Abstract:

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A series of novel Hydroxylated 9,10-anthraquinone derivatives were designed and synthesized as potential antitumor agents starting from the natural product Emodin. The structures of the compounds were identified by NMR, ESI-MS and elemental analysis. Their antitumor activities against KLE cell line were tested by MTT assay. Some of them were found to exhibit a cytotoxicity profile more potent than Emodin on KLE cell line.

Info:

Periodical:

Edited by:

Barry Tan

Pages:

294-296

DOI:

10.4028/www.scientific.net/AMM.108.294

Citation:

X. P. Wang and W. F. Xu, "Antitumor Activities of Hydroxylated 9,10-Anthraquinone Derivatives", Applied Mechanics and Materials, Vol. 108, pp. 294-296, 2012

Online since:

October 2011

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$35.00

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