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Antitumor Activities of Hydroxylated 9,10-Anthraquinone Derivatives

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Abstract:

A series of novel Hydroxylated 9,10-anthraquinone derivatives were designed and synthesized as potential antitumor agents starting from the natural product Emodin. The structures of the compounds were identified by NMR, ESI-MS and elemental analysis. Their antitumor activities against KLE cell line were tested by MTT assay. Some of them were found to exhibit a cytotoxicity profile more potent than Emodin on KLE cell line.

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Periodical:

Applied Mechanics and Materials (Volume 108)

Pages:

294-296

DOI:

https://doi.org/10.4028/www.scientific.net/AMM.108.294

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Online since:

October 2011

Authors:

Xing Po Wang, Wen Fang Xu

Keywords:

Antitumor Activities, Hydroxylated 9,10-Anthraquinone Derivative, Structural Confirmation

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© 2012 Trans Tech Publications Ltd. All Rights Reserved

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