In this study, for behavior of steel plate which subjected to uniform blast loading the general purpose finite element software ABAQUS, was used. The aim of this paper is to recognize the effect of stiffener configurations, boundary conditions, mesh dependency, load patterns, geometry of plates and damping on dynamic response of the plates. Special emphasis is focused on the evolution of mid-point displacements. The results show that stiffener configuration and boundary conditions have a significant influence on the response, while the effects of damping and load pattern on maximum response are negligible. The results obtained allow an insight into the effect of stiffener configurations and other parameters on the response of the plates under uniform blast loading.