Infrared and visible image fusion is an important precondition to realize target perception for unmanned aerial vehicles (UAV) based on which UAV can perform various missions. The details in visible images are abundant, while the target information is more outstanding in infrared images. However, the conventional fusion methods are mostly based on region segmentation, and then the fused image for target recognition can’t be actually acquired. In this paper, a novel fusion method of infrared and visible image based on target regions in discrete wavelet transform (DWT) domain is proposed, which can gain more target information and preserve the details. Experimental results show that our method can generate better fused image for target recognition.