Research of Curve-Fitting on RIA Dosage Reaction

Abstract:

This article, aiming at the problem of simulating a RIA (radioimmunoassay analysis) curve by function, analyzes the difference among four common fitting methods used to solve it. The methods include Log-Logit transform method, 3/2-time equation method, Spline function method and four-parameter Logistic curve method. We Make comparisons of different fitting methods by using FM-200 series gamma immune counter test a same set of standard sample and get a conclusion that four-parameter Logistic fitting method is the ideal one.

• Periodical: Applied Mechanics and Materials (Volumes 135-136)
• Pages: 747-752
• DOI: https://doi.org/10.4028/www.scientific.net/AMM.135-136.747
• Online since: October 2011
• Authors: Yan Chu, Hai Guang Wang, Chun Hua Deng, Yan Shao
• Keywords: Curve Fitting, Four-Parameter, Logistic Curve, RIA Analysis

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