The Preparation and Evaluation of the Combined Artificial Bone

Abstract:

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Every year, roughly two million patients worldwide sustain a bone grafting procedure to repair bone defects stemming from tumor, the wound, the infection, as well as other reasons [1, 2]. The bone transplantation is one of main methods to treat bone damages [3]. The gold standard is to use autologous bone or autograft [4]. However, both the need of the second surgery and morbidity at the extraction site [5-7] has been an incentive to search for alternative treatment. One of them is to form bone graft bone. Many materials have been widely chosen to form bone graft substitutes: metals, polymers, ceramics, dehydrate, and calcium phosphates [8-13]. Although these synthetic materials provide an immediate solution for many patients, their long-term performance is generally not satisfactory. This is often due to a mechanical property mismatch between the implant failure and tissue damage [14, 15]. The development of combined artificial bone with improved mechanical properties and enhanced biocompatibility calls for a biomimetic approach using natural bone as a guide.

Info:

Periodical:

Edited by:

Robert Zhu

Pages:

1-6

DOI:

10.4028/www.scientific.net/AMM.140.1

Citation:

K. Y. Mao et al., "The Preparation and Evaluation of the Combined Artificial Bone", Applied Mechanics and Materials, Vol. 140, pp. 1-6, 2012

Online since:

November 2011

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$35.00

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