The Preparation and Evaluation of the Combined Artificial Bone

Abstract:

Every year, roughly two million patients worldwide sustain a bone grafting procedure to repair bone defects stemming from tumor, the wound, the infection, as well as other reasons [1, 2]. The bone transplantation is one of main methods to treat bone damages [3]. The gold standard is to use autologous bone or autograft [4]. However, both the need of the second surgery and morbidity at the extraction site [5-7] has been an incentive to search for alternative treatment. One of them is to form bone graft bone. Many materials have been widely chosen to form bone graft substitutes: metals, polymers, ceramics, dehydrate, and calcium phosphates [8-13]. Although these synthetic materials provide an immediate solution for many patients, their long-term performance is generally not satisfactory. This is often due to a mechanical property mismatch between the implant failure and tissue damage [14, 15]. The development of combined artificial bone with improved mechanical properties and enhanced biocompatibility calls for a biomimetic approach using natural bone as a guide.

• Periodical: Applied Mechanics and Materials (Volume 140)
• Pages: 1-6
• DOI: https://doi.org/10.4028/www.scientific.net/AMM.140.1
• Online since: November 2011
• Authors: Ke Ya Mao, Fei Hu Zhou, Fu Zai Cui, Jiang Tao Li, Zi Shen Cheng, Peng Li, Zheng Wang, Ke Zheng Mao, Yang Wang
• Keywords: Combined Artificial Bone, Self-Setting, α-Calcium Sulphate Hemihydrate, β-Tricalcium Phosphate

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