Neural Respiratory Drive during CO2 Rebreathing Assessed by a Combined Esophageal Electrode Catheter

Kang Xin Tan; Dong Xiao Lu; Yuan Ming Luo

doi:10.4028/www.scientific.net/AMM.140.191

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HomeApplied Mechanics and MaterialsApplied Mechanics and Materials Vol. 140Neural Respiratory Drive during CO2 Rebreathing...

Neural Respiratory Drive during CO₂ Rebreathing Assessed by a Combined Esophageal Electrode Catheter

Abstract:

Assessment of neural respiratory drive is useful for diagnosis and management of breathing difficulty. The diaphragm is the most important muscle of respiration, therefore its electrical activity during spontaneously breathing could be used to reflect neural respiratory drive. In this study a catheter which was composed of 10 electrodes and two balloons was developed and was used to assess neural respiratory drive during CO₂ rebreathing in six healthy subjects. There was a good linear relationship between diaphragm EMG and end-tidal CO₂ (r = 0.98±0.01) during CO₂ rebreathing. Transdiaphragmatic pressure was also well correlated with end-tidal CO₂ during CO₂ rebreathing. We concluded that the combined catheter developed in this study can be used to assess neural respiratory drive.

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Periodical:

Applied Mechanics and Materials (Volume 140)

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191-194

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https://doi.org/10.4028/www.scientific.net/AMM.140.191

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Online since:

November 2011

Authors:

Kang Xin Tan, Dong Xiao Lu, Yuan Ming Luo

Keywords:

CO₂ Rebreathing, Combined Esophageal Electrode Catheter, Neural Respiratory Drive

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