Synthesis and Characterization of an Alendronate-Chitosan Conjugate

Abstract:

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The biomineral-binding alendronate-chitosan conjugate (Scheme 1) was developed as a novel drug delivery system. Alendronate was conjugated to the hydroxyl groups of chitosan, thereby maintaining the amino groups of chitosan intact. By means of FT-IR and 1H NMR, the characterization was conducted to confirm the successful synthesis of alendronate-chitosan conjugate.

Info:

Periodical:

Edited by:

Robert Zhu

Pages:

53-57

DOI:

10.4028/www.scientific.net/AMM.140.53

Citation:

X. H. Shao et al., "Synthesis and Characterization of an Alendronate-Chitosan Conjugate", Applied Mechanics and Materials, Vol. 140, pp. 53-57, 2012

Online since:

November 2011

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Price:

$35.00

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