Highland Plains People AVP Gene Polymorphism and the Relationship between Hypoxic Adaptation

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Objective To investigate the plateau plains of arginine vasopressin (AVP) gene polymorphism population and hypoxic adaptation in the relationship. Methods Polymerase chain reaction and restriction fragment length polymorphism method, the indigenous Tibetan population and plains Han Chinese AVP gene polymorphism detection and analysis of genotype and allele distribution. Results Showed that 150 cases of native Tibetans in +22959 sites GG, GT, TT distribution of genotype frequencies were 46%,50.1% and 3.3%, while the plain Han people 60. %, 37.3 %and 4.7%, the difference was statistically significant (P <0.05); Tibetan plateau alleles G, T in the distribution frequency of 67.4 %and 32.6,% and 82.2% and 17.8% plains of the Han people, the difference Statistically significant (P

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Periodical:

Edited by:

Robert Zhu

Pages:

63-67

DOI:

10.4028/www.scientific.net/AMM.140.63

Citation:

W. H. Li et al., "Highland Plains People AVP Gene Polymorphism and the Relationship between Hypoxic Adaptation", Applied Mechanics and Materials, Vol. 140, pp. 63-67, 2012

Online since:

November 2011

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$35.00

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