The V-cone flow meter is widely used to measure gas, liquid and high temperature steam in current industrial production. By applying the FLUENT software of CFD, a three-dimensional model about the V-cone flow meter is built. The effect of technical parameters on flow in the V-cone flow meter field has been studied by using computational fluid dynamics (CFD). The data fitting for empirical formula of the outflow coefficient was completed by using MATLAB software to provide some basis for the further production and exploration. The simulation outflow coefficient is relevant to the parameter of the effective diameter ratio , the diameter of pipe D, front-cone angle and back-cone angle .