The Application Research of Biological Materials in Meniscus Injuries

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Abstract:

The intervention means for rehabilitation of meniscus injury using artificial biomaterials were increasingly sophisticated, which provide brand new research directions for rehabilitation of meniscus injuries. However, it is difficult to select the desired implant due to existent a series of problems, including the biocompatibility, shape matching, adhesion, toughness, strength of artificial biological materials to human body in the process of specific practical application. Nowadays, main biological materials for meniscus injuries including hyaluronic acid, collagen, gelatin, poly hydroxyl acid, lactic acid, calcium Polyphosphate-accumulating, Polytetrafluoroethylene, carbon fiber reinforced polymer that is not absorbed, and so on. The stem cells were induced redirect directionally or gene modified by transforming growth factor beta 1. Make bone marrow mesenchymal stem cells differentiate into cartilage cells by adjusting the number of cell growth and differentiation, and being inoculated for biomaterial scaffold, which provides new research directions for meniscus injury rehabilitation.

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128-131

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April 2012

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© 2012 Trans Tech Publications Ltd. All Rights Reserved

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