Experiment Research of Diffuse Optical Tomography Imaging in Homogeneous Medium

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Abstract:

Given the time-domain measurement of picoseconds pulses and frequency-domain measurement of high-frequency modulation have limitations to realize, this paper introduces the experiment research which use square-wave modulation laser source as incident light source of the diffusion optical tomography in homogeneous medium. Based on the finite-element method, the forward model can be established. The analytical solution of the homogeneous medium can obtained from the derivation of the diffusion equation, after that, we build the optical experiment platform, derive the experimental solution from the platform. Finally, the consistent result is obtained by the comparison of the simulation, the analytical solution and the experimental solution. The result clearly demonstrated the accuracy and effectiveness of the proposed method which use square-wave modulation laser source as incident light source to measure the light intensity.

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561-565

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August 2012

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© 2012 Trans Tech Publications Ltd. All Rights Reserved

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[1] F. E. W. Schmidt, M. E. Fry, E. M. C. Hillman, J. C. Hebden, and D. T. Delpy, A 32-channel time-resolved instrument for medical optical tomography, Review of Scientific Instruments, vol. 71, pp.256-265, January (2000).

DOI: 10.1063/1.1150191

Google Scholar

[2] R. Aronson, R. L. Barbour, and J. Lubowsky, Modern mathematical methods in transport theory, Basel, Birkhauser, (1991).

Google Scholar

[3] S. R. Arridge, Optical tomography in medical imaging, Inverse Problem, vol. 15, pp.41-93, (1999).

Google Scholar

[4] M. A. Oleary, D. A. Boas, B. Chance, and A. G. Yodh, Experimental images of heterogeneous turbid media by frequency-domain diffusing-photon tomography, Optics Letters, vol. 20, pp.426-428, March (1995).

DOI: 10.1364/ol.20.000426

Google Scholar

[5] W. T. Li, H. N. Wang, and Z. Y. Qian, Optimization Approach to Inverse Problems in Near-infrared Optical Tomography, Journal of Biomedical Enginering, vol. 25, pp.264-269, April 2008 (in Chinese).

Google Scholar

[6] T. O. McBride, A parallel-detection frequency-domain near-infrared tomography system for hemoglobin imaging of the breast in vivo, Review of Scientific Instruments, vol. 72, pp.1817-1724, (2001).

DOI: 10.1063/1.1344180

Google Scholar

[7] K. X. Xu, F. Gao, and H. J. Zhao, Biomedical Photonics. BeiJing, Sciences Publishing House, 2007 (in Chinese).

Google Scholar