Structure Design and Turbulence Simulation of Disaggregation Pipe in Dry Powder Inhaler

Abstract:

This paper provides structure design of the disaggregation pipe in active dry powder inhaler, to achieve the maximization of active pharmaceutical ingredient diffusing and disaggregating from its carriers, uses computational fluid dynamics method in CFX to simulate the turbulence in the structure, observes airflow velocity, turbulent kinetic energy and shear strain rate to evaluate the effect of diffusion and disaggregation and operate Lagrange particle tracking method in the structure to obtain particles’ superficial velocity, volume fraction and shear stress, providing a theoretical basis for structure design of the disaggregation pipe in active dry powder inhaler.

• Periodical: Applied Mechanics and Materials (Volumes 220-223)
• Pages: 1727-1731
• DOI: https://doi.org/10.4028/www.scientific.net/AMM.220-223.1727
• Online since: November 2012
• Authors: Xian Kui Zhang, Tian Yi Liu
• Keywords: Computational Fluid Dynamics (CFD), Disaggregation Pipe, Dry Powder Inhaler, Structure Design, Turbulence

References

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