Research Progress on the Anti-Leukemia Effect of Lycorine

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Abstract:

Lycorine is a kind of natural alkaloid extracted from Amaryllidaceae that has shown various pharmacological effects. Recent studies have focused on the potential antitumor activity of lycorine. The inhibition effects of lycorine on the cell proliferation of leukemia HL-60 cells, K562 cells, chronic lymphocytic leukemia, U937 cells and structure-activity studies on the lycorine pharmacophore in leukemia cells were summarized in the article. The review of pharmacological effects and structure-activity on leukemia of lycorine can provide a reference for the further development and utilization on the kind of natural products.

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3193-3196

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September 2013

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© 2013 Trans Tech Publications Ltd. All Rights Reserved

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