New Progress about Apoptosis Factors of Tumor Cell

Article Preview

Abstract:

The development of tumor is not only results of the uncontrolled cell proliferation, the differentiation and cell abnormalities, but also relates to apoptosis imbalance. Inducing tumor cell apoptosis has become an important means of clinical applications on cancer treatment. Apoptosis of tumor cells is affected by a variety of gene regulation, including some oncogenes and tumor suppressor genes which are related to cell proliferation. Focusing on the three basic ways of apoptosis: death receptor pathway, the mitochondrial pathway, and endoplasmic reticulum stress pathway, This paper summarizes the research progress of appoptosis factors for the past few years and provides information and ideas for finding out effective anticancer drugs which have key anti-cancer factors as target points.

You might also be interested in these eBooks

Info:

Periodical:

Pages:

3242-3245

Citation:

Online since:

September 2013

Export:

Price:

Permissions CCC:

Permissions PLS:

Сopyright:

© 2013 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

[1] Yaoxian Wang, Huinan Hao, Xiuwei Chen, Hui Yu, Ge Lou, Xiaoke Wu. Chinese Journal of Traditional Medical Science and Technology, Vol. 1 (2013), P. 37-39. (In Chinese).

Google Scholar

[2] Dawei LU, Hongying YANG. Journal of Modern Oncology, Vol. 20 (6) ( 2012), P. 1281-1285. (In Chinese).

Google Scholar

[3] Sheltty S, Gladden J S. Henson E S, et al. Apoptosis, Vol. 7 (5) (2009), P. 413-420.

Google Scholar

[4] Tafuku S, Matsuda T, Kawakami H, et al. Eur J Haematol, Vol. 76 (1) (2006), P. 64-74.

Google Scholar

[5] Duiker EW; Metjer A; van der Bih AR et al. Br J Cancer, Vol. 104 (8) (2011), P, 1278-1287.

Google Scholar

[6] Wu X X, Jin X H, Zeng Y, et al. Cancer Sci, Vol. 98 (12) (2007), P. 1969-(1976).

Google Scholar

[7] Kim Y J, Lee S A, Myungsc, et al. Mol Cell Bioehem, Vol. 1 (2012), P. 33-43.

Google Scholar

[8] Hitomi J, Katayama T, Eguchi Y, et al. J Cell Biol, Vol. 165 (2004), P. 347-356.

Google Scholar

[9] Wu L F, Wei B L, Guo Y T, et al. Int J Mol Med, Vol. 10 (2012), P. 3892.

Google Scholar

[10] Lin H H, Chen J H, Huang C C, et al. Int J Cancer, Vol. 120 (11) (2007), P. 2306-2316.

Google Scholar

[11] Miao Zhu, Xuejiang Wang. Tumer, Vol. 22 (6) (2002), P. 522-526. (In Chinese).

Google Scholar

[12] Wei Guo, Huixiang Li. China Prac Med, Vol. 21 (3) (2008), P. 192-194. (In Chinese).

Google Scholar

[13] Zhang Wei. The cloning, expression of C-terminal truncated human AIF molecules and their apoptosis induction on HeLa cells. Xi An. The Fourth Military Medical University. (2007). P. 65-69. (In Chinese).

Google Scholar