Assessment and Prediction of Joint Toxicity of Aniline Derivatives

Hui Lin Ge; Shu Shen Liu; Hong Qiu Yuan; Gui Hao Yin; Yi Xie; Ling Yun Mo

doi:10.4028/www.scientific.net/AMM.448-453.217

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HomeApplied Mechanics and MaterialsApplied Mechanics and Materials Vols. 448-453Assessment and Prediction of Joint Toxicity of...

Assessment and Prediction of Joint Toxicity of Aniline Derivatives

Abstract:

The joint toxicity of aniline, 2-methylaniline, 3-methylaniline, 4-methylaniline, 2-nitroaniline, 3-nitroaniline, 4-nitroaniline, 2-chloroaniline, 3-chloroaniline, and 4-chloroaniline on photobacterium were predicted and evaluated by using concentration addition (CA) and independent action (IA) models, and joint effect indices including toxic units, additive index, mixture toxicity index, and similarity parameter. The tested mixture presented synergism.