On-Site Monitoring of Steroid Hormones in Environmental Waters with a Low-Cost, Integrated Polymer Lab-on-Chip Device

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Abstract:

Routine analysis of steroid hormones in environmental water samples demands for cost-effective tools that can detect multiple targets simultaneously. This study reports a high-throughput polymer platform integrated to polymer optical sensors for on-site monitoring of hormones in water. This opto-microfluidic device concept is fully compatible to low-cost fabrication methods. A competitive chemiluminescence immunoassay was performed onto gold thin film coated chambers, and a detection resolution of roughly 0.2 ng/mL was obtained using 17β-estradiol as the model target. Furthermore, the integrated polymer platform showed good recovery for the estradiol target when spiked in surface water samples.

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396-401

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October 2013

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© 2014 Trans Tech Publications Ltd. All Rights Reserved

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