Implementation and Validation of ECG-Derived Respiration with QRS Characteristics

Abstract:

This study presents a method for reconstructing respiration signals from ECG tracings based on average electrical-cardiac-axis theory with heart rate variability. The algorithm is simplified to use QRS characteristic points and subsequent spectrum analysis. The experiments were conducted on eight healthy patients during rest with spontaneous (voluntarily) and paced breathings. Five QRS characteristic series are constructed, and the corresponding electrocardiography (ECG)-derived respiration (EDR) is compared with measured data. The experiment results show the R-Q-S series-derived respiration exhibited superior correlation with the original respiration from the perspective of breathing frequency.

• Periodical: Applied Mechanics and Materials (Volumes 479-480)
• Pages: 457-462
• DOI: https://doi.org/10.4028/www.scientific.net/AMM.479-480.457
• Online since: December 2013
• Authors: Shyan Lung Lin, Ching Kun Chen, Ching Sheng Chien
• Keywords: Breathing Frequency, ECG, EDR, QRS Characteristic Series, Respiratory Signal

References

[1] C.C. Chiu, C.M. Chuang and C.Y. Hsu: Int. J. Wavelets Multi. Vol. 7 (2009), p.341.

[2] C.K. Chen, C.L. Lin, C.T. Chiang and S.L. Lin: Inform. Sci. Vol. 193 (2012), p.125.

[3] J. Nyboer, M.M. Kreider, and L. Hannapel: Circulation Vol. 2 (1950), p.811.

[4] R.S. Hoon, V. Balasubramanian, S.C. Tiwari, O.P. Mathew, A. Behl, S.C. Sharma, and K.S. Chadha: Br Heart J, Vol. 39 (1977), p.61.

DOI: 10.1136/hrt.39.1.61

[5] L.A. Geddes: Med. Biol. Eng. Comput. Vol. 22 (1984), p.90.

[6] F. Pinciroli, G. Pozzi and R. Rossi, Processing Electrocardiograms Towards Respiratory Signals, volume 1 of Proc. of the Annual International Conf. of the IEEE (1988).

DOI: 10.1109/iembs.1988.94445

[7] L.E. Baker: IEEE Eng. in Med. and Biol., Vol. 8 (1989), p.50.

[8] J.P. Saul, D.T. Kaplan and R.I. Kitney, Nonlinear Interactions Between Respiration and Heart Rate: Classical Physiology or Entrained Nonlinear Oscillators, Proceedings of Computers in Cardiology, (1988) Sep. 25; Washington, DC.

DOI: 10.1109/cic.1988.72621

[9] L. Zhao, S. Reisman and T. Findley, Derivation of Respiration from Electrocardiogram during Heart Rate Variability Studies, Proceedings of Computers in Cardiology, (1994) Sep. 25; Bethesda, MD.

DOI: 10.1109/cic.1994.470251

[10] G. B. Moody. R.G. Mark, M.A. Bump, J.S. Weinstein, A.D. Berman, J.E. Mietus and A.L. Goldgerger, Clinical Validation of the ECG-derived Respiration (EDR) Technique, Proceedings of Computers in Cardiology, (1986) Sep. 25; Washington, DC.

[11] M.A. Sackner, Monitoring of ventilation without physical connection to the airways: a review. Proceedings of the III ISAM (1979).

[12] G.B. Moody, R. Mark, A. Zocoola and S. Mantero, Derivation of respiratory signals from multi-lead ECGs, Proceedings of Computers in Cardiology, (1985) Sep. 25; Washington, DC.

[13] H. Nazeran, K. Behbehani, F.C. Yen and P. Ray, Reconstruction of Respiratory Patterns from Electrocardiographic Signals, Proc. of the 2nd International Conference on Bioelectromagnetism, (1998) Feb 15; Melbourne, Vic.

DOI: 10.1109/icbem.1998.666454

[14] M. Raciti, P. Pisani, C. Carpeggiani, S. Ruschi, G. Kraft, R. Francesconi, G. Membretti and C. Marchesi, Circadian dynamic of respiratory parameters from ambulatory monitoring, Proceedings of Computers in Cardiology, (1994) Sep. 25; Bethesda, MD.

DOI: 10.1109/cic.1994.470125

[15] T.E. Brown, L.A. Beightol, J. Koh and D.L. Eckberg, J Appl. Physiol. Vol. 75 (1993), p.2310.

[16] C. Schäfer, M.G. Rosenblum, J. Kurths and H. Abel, Nature, Vol. 392 (1998), p.239.

[17] E. Toledo, M.G. Rosenblum, J. Kurths, S. Akselrod and Cardirespiratory synchronization: is it a real phenomenon? Proceedings of Computers in Cardiology, (1999) Sep. 26; Hannover.

DOI: 10.1109/cic.1999.825950

[18] D. Caggiano and S. Reisman, Respiration derived from the electrocardiogram: a quantitative comparison of three different methods, Proc. of the IEEE 23rd Annual Northeast Bioengineering Conference, (1996) Mar. 14; New Brunswick, NJ.

DOI: 10.1109/nebc.1996.503238

[19] A. Travaglini, C. Lamberti and J. DeBie, M. Ferri, Respiratory signal derived from eight-lead ECG, Proc. of Computers in Cardiology, (1998) Sep. 13; Cleveland, OH.

DOI: 10.1109/cic.1998.731718

[20] B. Mazzanti, C. Lamberti and J. de Bie, Validation of an ECG-derived Respiration Monitoring Method, Proc. of Computers in Cardiology, (2003) Sep. 21; Thessaloniki Chalkidiki, Greece.

DOI: 10.1109/cic.2003.1291230

[21] C.S. Chien: The Study of the Relationship between ECG and Respiratory Signals, (M.S. Thesis, Feng Chia University, Taiwan 2005).