Toxic Effects of Toxaphene for Goldfish

Abstract:

Toxaphene is an organochlorine insecticide, widely used in cereals, vegetables, fruits, tea and other pests. However, in killing pests, increasing agricultural production, while toxaphene aquatic creatures threat. In order to enrich aquatic organisms toxicological data, evaluate the risk to aquatic organisms toxaphene healthy growth, we use the traditional toxicological approach to study the toxic effects of toxaphene goldfish (Carassius auratus)'s. Study 5 toxaphene concentration 7d goldfish exposed catalase (CAT), superoxide dismutase (SOD), acetylcholinesterase (TChE), glutathione peroxidase (GSH-PX), malondialdehyde (MDA) effects, the results showed that: toxaphene in 0.1,0.2,0.3,0.4, 0.5 μg / L in five concentrations, these five enzymes promoting effect, with more toxaphene concentration high, goldfish liver CAT activity is stronger, the stronger the brain and liver SOD activity, the activity of the brain TChE weaker, the stronger the brain activity of GSH-PX, and the contrast with the blank, P <0.01, illustrate the five enzymes do toxaphene toxicity testing of biomarkers.

• Periodical: Applied Mechanics and Materials (Volumes 641-642)
• Pages: 1195-1199
• DOI: https://doi.org/10.4028/www.scientific.net/AMM.641-642.1195
• Online since: September 2014
• Authors: Song Mei Wang*, Xiang Yang Wu, Hai Xu, Cong Wei Lu, Yun Xiao Xu, Fan Zhang
• Keywords: Biological Markers, Enzyme, Goldfish, Toxaphene

References

[1] ButingA. Insecticidal Compositions Comprising Chlorinated Camphene [P]. USA: 2565471, 1951-08-28.

[2] Vetter W, Oehme M. Toxaphene analysis and the environmental fate of congeners[C]/New Types of persistent Halogenated Compounds Paasivirta J, ed Berlin : Springer Press, 2003(3): 237～287.

DOI: 10.1007/3-540-48915-0_9

[3] Voldner A, Ames N, Saleh A. Toxaphene , a complex mixture polychloroterpenes and a major insecticide[J]. Science, 1979, 205(5): 591-593.

DOI: 10.1126/science.377495

[4] Vasseur P, Cossu-Leguille C. Linking molecular interactions to consequent effects of persistent organic pollutants(POPs) upon populations[J]. Chemosphere, 2006, 62(7): 1033-1042.

DOI: 10.1016/j.chemosphere.2005.05.043

[5] Van den Berg M, Birnbaum L S, Denison M, et al. The 2005 World Health Organization reevaluation of human and mammalian toxic equivalency factors for dioxins and dioxin-like compounds [J]. Toxical Sci, 2006, 93(2): 223-241.

DOI: 10.1093/toxsci/kfl055

[6] Sies H. Glutathione and its role in cellular functions [J]. Free Radic Biol Med, 1999, 27(9-10): 916-921.

DOI: 10.1016/s0891-5849(99)00177-x

[7] Halliwell B, Gutteridge J. Free radicals in biology and medicine [M]. Oxford University Press, New York, 1999, 105-245.