Found Robust Calibration Model in Fermentation Process by Combining Different Sample Sets

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Abstract:

Robust calibration model is the key factor for spectroscopic measurement. The commonly used way is build calibration model by crude samples collected from process. There are two deficiencies in fermentation processes in that: matrix effects variation always existed for different batch of fermentation and, chance correlation is sure existed which spoil robust of calibration model. In the research being presented, method of overcoming the weakness is examined. By combing the standard analyte and fermentation broth and spiking solvend, the calibration model can correlate specific spectral features only with the measured analyte concentrations so have good robustness.

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372-375

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October 2014

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© 2014 Trans Tech Publications Ltd. All Rights Reserved

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[1] Payal Roychoudhury, Linda M. Harvey, Brian McNeil: Analytica chimica acta Vol. 561 (2006), p.218–224.

Google Scholar

[2] Sergio Armenta, Salvador Garrigues, Miguel de la Guardia, Philippe Rondeau: Analytica chimica acta Vol. 545 (2005), p.99–106.

DOI: 10.1016/j.aca.2005.04.057

Google Scholar

[3] Henri Kornmann, Martin Rhiel, Christopher Cannizzaro, Ian Marison, Urs von Stockar: Biotechnology and bioengineering Vol. 82(2003), pp.702-709.

DOI: 10.1002/bit.10618

Google Scholar

[4] Ennis L. Veale, Joseph Irudayaraj and Ali Demirci: Biotechnology progress, Vol. 23 (2007), pp.494-500.

Google Scholar

[5] Jonas Schenk, Ian W. Marison, Urs von Stockar: Analytica chimica acta Vol. 591 (2007), p.132–140.

DOI: 10.1016/j.aca.2007.03.056

Google Scholar

[6] Mark R. Riley, Heather M. Crider: Talanta, Vol. 52 (2000), p.473–484.

Google Scholar