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HomeApplied Mechanics and MaterialsApplied Mechanics and Materials Vol. 729L-Proline-Catalyzed Synthesis of Amino Thiazoles

L-Proline-Catalyzed Synthesis of Amino Thiazoles

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Abstract:

An L-proline-catalyzed synthesis of amino thiazoles is described here. Amides and 2-mercapto thiazoles were used as the starting reagents. Various reaction conditions were screened, and the scope of various amides and 2-mercapto thiazoles has been examined. Most of the substrates gave high yields. Compared with traditional synthetic methods with transition metal as catalyst, this protocol uses organocatalyst L-proline. It will reduce environment pollution and save the synthetic cost.

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Materials, Mechanics and Information Engineering

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Periodical:

Applied Mechanics and Materials (Volume 729)

Pages:

79-82

DOI:

https://doi.org/10.4028/www.scientific.net/AMM.729.79

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Online since:

January 2015

Authors:

Zhi Jie Li, Dong Ming Lu, Li Guo, Qing Le Zeng

Keywords:

Amino Thiazoles, Catalysis, Green Process, Mercapto Thiazoles, Proline

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© 2015 Trans Tech Publications Ltd. All Rights Reserved

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