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HomeApplied Mechanics and MaterialsApplied Mechanics and Materials Vol. 729Synthesis of α-Hydroxy Amides

Synthesis of α-Hydroxy Amides

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Abstract:

α-Hydroxy amides are a class of important intermediates in organic synthesis. It plays an important role in the field of science and medicine. However, the preparation methods of α-hydroxy amides are relatively few, and they are usually enzyme-or Lewis acid-catalyzed reactions. These types of methods are not ideal in operation, yield and/or stereoselectivity. We found a new way to synthesize α-hydroxy amides by transforming amino acids into α-hydroxyl acids, and then by amination of the α-hydroxy acids.

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Materials, Mechanics and Information Engineering

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Periodical:

Applied Mechanics and Materials (Volume 729)

Pages:

83-86

DOI:

https://doi.org/10.4028/www.scientific.net/AMM.729.83

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Online since:

January 2015

Authors:

Dong Ming Lu, Zhi Jie Li, Feng Jiao Li, Qing Le Zeng*

Keywords:

Diazotization, Intermediates, Organic Synthesis, α-Hydroxy Acids, α-Hydroxy Amides

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© 2015 Trans Tech Publications Ltd. All Rights Reserved

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