The field tests of interaction between structure and foundation were carried out in the present work which was quite different from the traditional divided method. The field experiments were done by using 20 pressure box and 3 inductance magnet rings in each survey hole. Through the tests data the mechanism of the foundation pressure and the distribution of layer settlement were studied. It is shown that there is an ultimate value as to the contribution of upper structure stiffness. The foundation pressure increases with the construction of building. But it will lead to a steady value from some floor to the top. And in the center of the foundation the foundation pressure is the biggest. As to the layer Settlement, the settlement decreases with the increasing of the depth. The Settlement and different settlement of natural foundation is the key to choose the type of their foundations.