Effect of very Low Frequency Electromagnetic Radiation on Acetylcholine Esterase Activity

Abstract:

Acetylcholinesterase (AChE) is the enzyme that controls the acetylcholine (ACh) concentrations in cholinergic synaptic clefts by hydrolyzing ACh to choline and acetate. In this paper, we investigate the effect of very low frequency (VLF) electromagnetic field (EMF) radiation on AChE activity. AChE was exposed to VLF-EMFs with electric field intensity ranged from 0 to 200V/m and exposure time ranged from 0 to 120min. The results demonstrated that the VLF-EMF increased enzyme activity when the intensity ranged from 80V/m to 100V/m as well as exposure time ranged from 60min to 80min. And the AChE activity decreased when the intensity ranged from 120V/m to 140V/m and exposure time ranged from 20min to 120min. Thus, those results are significant in clinical treatments.

• Periodical: Advanced Materials Research (Volumes 1004-1005)
• Pages: 827-836
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.1004-1005.827
• Online since: August 2014
• Authors: Hong Wang, Zheng Wei Du, Pei Dong Guo, Yun Ming Tang*
• Keywords: AChE, AChE Activity, Electric Field, Exposure, VLF-EMFs

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