Bioactive Calcium Silicate Coating of Titania Nanotubes for Controlled Drug Release

Ping Li; Zhang Wang; Fei Luo; Xiu Feng Xiao

doi:10.4028/www.scientific.net/AMR.1033-1034.1005

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HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 1033-1034Bioactive Calcium Silicate Coating of Titania...

Bioactive Calcium Silicate Coating of Titania Nanotubes for Controlled Drug Release

Abstract:

A novel and facile process called “alternative loop immersion method” formed bioactive and biocompatible Zn-doped calcium silicate coating over the drug-loaded titania nanotube arrays to improve the properties of drug release. The samples were characterized by scanning electronic microscope (SEM), x-ray diffraction (XRD) and fourier transform infrared (FT-IR). The results show that TNTs modified by Zn-doped calcium silicate coating possess improved drug release characteristics with reduced burst release (from 83% to 66%) and prolonged drug release (from 11 days to over 15 days). This approach provides an alternative to tailor the surface of TNTs and offer considerable propects for diverse biomedical applications.

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Periodical:

Advanced Materials Research (Volumes 1033-1034)

Pages:

1005-1008

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.1033-1034.1005

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Online since:

October 2014

Authors:

Ping Li, Zhang Wang, Fei Luo, Xiu Feng Xiao*

Keywords:

Alternative Loop Immersion Method, Calcium Silicate, Drug Release, Titania Nanotube, Zn-Doped

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* - Corresponding Author

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