Synthesis of Three Different Types of Chalcone Derivatives

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Abstract:

Three chalcone derivatives were synthesized by the reaction of acetophenone with dimethylamino benzaldehyde, vanillin, diphenyl formaldehyde, respectively. The results showed that: A yield of 80.4% was obtained by the reaction of acetophenone and dimethylamino benzaldehyde in ethanol as solvent, 10% NaOH solution as catalyst at room temperature. A yield of 25.0% was obtained by the reaction of acetophenone and vanillin in ethanol as solvent, a mixed glacial acetic acid and hydrochloric acid as the catalyst, adding 10% KOH solution for dehydration by heating after the reaction at room temperature. A yield of 76.3% was obtained by the reaction of acetophenone and diphenyl formaldehyde in ethanol as solvent, 10% NaOH solution as catalyst at room temperature. Acid was used as the appropriate catalyst when chalcone derivatives were synthesized by aldehyde with hydroxy.

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Advanced Materials Research (Volumes 1033-1034)

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81-84

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October 2014

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© 2014 Trans Tech Publications Ltd. All Rights Reserved

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